Genomic Surveillance of Multidrug-Resistant Organisms Based on Long-Read Sequencing

Medicine, Infectious Diseases, Environmental and Public Health, Life Sciences, Genetics, Microbiology,
genomic surveillance   multidrug-resistant organisms   long-read sequencing   nanopore sequencing   MLST   WGMLST   WGS  

Genomic Surveillance of Multidrug-Resistant Organisms Based on Long-Read Sequencing Research Background Multidrug-resistant organisms (MDROs) are a significant global public health threat. These organisms exhibit resistance to multiple antibiotics, making infections challenging to treat and increasing healthcare costs. To effectively monitor and co...

Century-Old Herbarium Specimen Provides Insights into Pierce’s Disease of Grapevines Emergence in the Americas

Medicine, Infectious Diseases, Life Sciences, Botany, Microbiology,
Pierce's disease   herbarium specimen   genome sequencing   pathogen introduction   historical genomics  

Summary of the Academic Paper Report on “Century-Old Herbarium Specimen Provides Insights Into Pierce’s Disease of Grapevines Emergence in the Americas” Introduction Pierce’s Disease (PD) of grapevines, caused by the bacterial subspecies Xylella fastidiosa subsp. fastidiosa (Xff), poses a severe threat to the viticulture industry. However, its geog...

Metabolite-Level Regulation of Enzymatic Activity Controls Awakening of Cyanobacteria from Metabolic Dormancy

Life Sciences, Cell Biology, Biochemistry, Bioengineering, Microbiology,
cyanobacteria   metabolic dormancy   enzyme activity   metabolite regulation   resuscitation mechanism  

Highlights of the Study: Metabolite-Level Regulation of Cyanobacteria Awakening from Dormancy Study Title: “Metabolite-level regulation of enzymatic activity controls awakening of cyanobacteria from metabolic dormancy” Published in Current Biology (January 6, 2025), this study, led by Sofía Doello, involves researchers from the University of Tübing...

Alkaloids are Associated with Increased Microbial Diversity and Metabolic Function in Poison Frogs

Life Sciences, Biochemistry, Microbiology,
alkaloids   poison frogs   microbial diversity   metabolic function   skin microbiome   bacterial communities   nitrogen metabolism  

Analysis of the Influence of Alkaloids on Frog Skin Microbiomes and Their Metabolic Functions Background and Significance Poison frogs (family Dendrobatidae) are amphibians with unique defense mechanisms, as their skin is rich in alkaloids, which are known for their broad-spectrum antimicrobial properties. However, the ways these alkaloids affect t...

Revolutionary Self-Powered Transducing Mechanism for Long-Lasting and Stable Glucose Monitoring: Achieving Selective and Sensitive Bacterial Endospore Germination in Microengineered Paper-Based Platforms

Engineering, Electrical Engineering, Medicine, Endocrinology, Life Sciences, Bioengineering, Microbiology,
glucose monitoring   self-powered transduction   bacterial spore germination   microengineered platforms   diabetes management  

Revolutionary Self-Powered Glucose Monitoring Mechanism: Microengineered Paper-Based Platform with Microbial Spores Academic Background Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels, which can lead to severe complications such as cardiovascular diseases, retinopathy, kidney failure, and neuropathy. The glob...

Fiber Optics-Based Surface Enhanced Raman Spectroscopy Sensors for Rapid Multiplex Detection of Foodborne Pathogens in Raw Poultry

Chemistry, Analytical Chemistry, Engineering, Electrical Engineering, Medicine, Infectious Diseases, Life Sciences, Bioengineering, Microbiology,
Surface Enhanced Raman Spectroscopy   Foodborne Pathogens   Raw Poultry   Multiplex Detection   Fiber Optics Sensor   Rapid Detection   Food Safety  

Fiber Optics-Based Surface Enhanced Raman Spectroscopy Sensors for Rapid Multiplex Detection of Foodborne Pathogens in Raw Poultry Academic Background Foodborne illnesses are a significant global public health challenge, with Salmonella being one of the leading pathogens causing such diseases. In the United States alone, Salmonella results in 1.35 ...