Cotton Population-Level DNA Methylation Polymorphism Study Reveals Epigenomic Contributions to Complex Traits Background and Research Motivation In recent decades, genome and genetic diversity have been extensively studied through genome-wide association studies (GWAS), providing a theoretical foundation for understanding crop trait variations. How...

Deep Learning-Driven Protein Design: Generating Functional Protein Sequences Using Conditional Diffusion Models Proteins are at the core of life sciences research and applications, offering countless possibilities due to their diversity and functional complexity. With advancements in deep learning technologies, protein design has reached a new pinn...

Deciphering the Topological Landscape of Glioma: A Study Based on a Network Theory Framework Glioma stem cells (GSCs) are recognized as key factors in glioma recurrence and treatment resistance, making them an important focus for new therapeutic approaches. However, the limited understanding of the role of GSCs in the hierarchy of glioma has sparke...

Stem Cell Transplantation Extends the Reproductive Lifespan of Naturally Aging Cynomolgus Monkeys Background of the Study The ovary is a crucial organ for female reproduction and health, responsible for producing oocytes and secreting sex hormones. As women age, ovarian reserves gradually decline, eventually leading to menopause, which brings about...

Study of Somite Formation Model Based on Microfluidic System Background and Research Motivation The formation of somites plays a crucial role in vertebrate embryonic development, significantly influencing the layout and functionality of the embryonic musculoskeletal system. Somite formation involves the segmentation of bilateral presomitic mesoderm...