Precision Imaging of Cardiac Function and Scar Size in Acute and Chronic Porcine Myocardial Infarction Using Ultral-high-field MRI

Precision Imaging of Cardiac Function and Scar Size in Acute and Chronic Porcine Myocardial Infarction Using Ultral-high-field MRI

Medicine, Medical Imaging, Cardiovascular System, Life Sciences, Biophysics,
ultrahigh field   myocardial infarction   cardiac function   porcine model   MRI   scar detection  

Precision Imaging of Cardiac Function and Infarct Scar Size: A Study with Ultrahigh-Field MRI in Acute and Chronic Porcine Models of Myocardial Infarction Research Background Cardiac magnetic resonance imaging (MRI) is an accurate and highly reproducible technique for assessing cardiac function and volume. In recent years, ultrahigh-field (UHF) MRI...

Inhibition of S6K Lowers Age-Related Inflammation and Increases Lifespan Through the Endolysosomal System

Medicine, Rheumatology and Immunology, Geriatrics, Life Sciences, Cell Biology, Biochemistry, Immunology, Genetics, Biophysics,
S6K   inflammation   lifespan   endolysosomal system   autophagy  

Inhibition of S6K Reduces Age-Related Inflammation and Extends Lifespan through the Endosomal-Lysosomal System Research Background and Problem Description As organisms age, chronic low-grade inflammation (inflammaging) and declined immune function (immunosenescence) become important pathological foundations of many diseases in the elderly, such as ...

Fluorescence Molecular Tomography Based on Group Sparsity Priori for Morphological Reconstruction of Glioma

Information Science, Computer Science, Artificial Intelligence, Medicine, Medical Imaging, Oncology, Life Sciences, Biophysics,
Group Sparsity   Fluorescence Molecular Tomography   Glioma   Morphological Reconstruction   Imaging   High Scattering   Tumor Research  

Report on the Study of Fluorescence Molecular Tomography for Morphological Reconstruction of Glioma Based on Group Sparsity Priors 1. Academic Background and Research Motivation Fluorescence Molecular Tomography (FMT) is an important tool in life sciences that allows non-invasive real-time three-dimensional (3D) visualization of fluorescence source...

Near-Infrared Window II Fluorescence Image-Guided Surgery of High-Grade Gliomas Prolongs the Progression-Free Survival of Patients

Near-Infrared Window II Fluorescence Image-Guided Surgery of High-Grade Gliomas Prolongs the Progression-Free Survival of Patients

Medicine, Neurosurgery, Medical Imaging, Oncology, Life Sciences, Biophysics,
Near-Infrared Window II   Fluorescence Image-Guided Surgery   High-Grade Gliomas   Progression-Free Survival   Surgical Outcome  

Near-Infrared Window II Fluorescence Imaging-Guided Surgery Prolongs Progression-Free Survival for High-Grade Glioma Patients Research Background High-grade glioma (HGG) is the most common malignant primary tumor in the central nervous system, with glioblastoma (GBM) having the worst prognosis. To improve the treatment outcomes for GBM patients, in...

Bidirectional Epigenetic Editing Reveals Hierarchies in Gene Regulation

Medicine, Life Sciences, Cell Biology, Immunology, Genetics, Biophysics,
Gene Regulation   Epigenetics   CRISPR Technology   Genetic Interactions   Transcription Factors  

Bidirectional Epigenetic Editing Reveals Hierarchies in Gene Regulation Background and Research Motivation In the human genome, the role of non-coding elements such as enhancers in gene regulation is widely recognized. However, current CRISPR interference methods still have some limitations in studying non-coding elements and genetic interactions. ...