Study of Mathematical Models for Tumor Growth – Exploring Glioma Extension Using Longitudinal Magnetic Resonance Imaging A recent article published in the IEEE Transactions on Biomedical Engineering presents a systematic study on the mathematical modeling and growth patterns of gliomas (glioma). This research was conducted by Birkan Tunç, David A. ...

Comparison of Acoustic Patterns and Microbubble Delivery Strategies in Large-Volume Drug Delivery Mediated by Focused Ultrasound for Blood-Brain Barrier Opening Background Diffuse Intrinsic Pontine Glioma (DIPG) is the most common and lethal brainstem tumor in children. Due to the usually intact blood-brain barrier (BBB) in DIPG, drug penetration i...

Near-Infrared Window II Fluorescence Imaging-Guided Surgery Prolongs Progression-Free Survival for High-Grade Glioma Patients Research Background High-grade glioma (HGG) is the most common malignant primary tumor in the central nervous system, with glioblastoma (GBM) having the worst prognosis. To improve the treatment outcomes for GBM patients, in...

The research results, completed in collaboration by many scientists including Lishu Chen, Qinghui Qi, and Xiaoqing Jiang, were published in the groundbreaking journal Cancer Discovery. The report detailed how phosphocreatine (PCr) promotes the growth of glioblastoma (GBM) by stabilizing bromodomain-containing protein 2 (BRD2). This discovery provid...

Research Report on the Regulation of Neuron-Glioma Interactions by CHD2 in Pediatric Gliomas Background High-grade gliomas (HGG) are fatal diseases in both adult and pediatric patients. Recent studies have shown that neuronal activity can promote the progression of various high-grade glioma subgroups. However, the epigenetic mechanisms regulating t...