Dual Functions of Pericytes and Perivascular Fibroblasts in Cerebrovascular Regeneration After Stroke Academic Background Stroke is one of the leading causes of death and disability worldwide. Current therapeutic interventions are mostly limited to acute thrombolytic treatment or thrombectomy, followed by long-term rehabilitation. However, the long...

Inferring Latent Neural Circuits from Heterogeneous Neural Responses During Cognitive Tasks Academic Background In cognitive tasks, higher cortical areas of the brain (such as the prefrontal cortex, PFC) are responsible for integrating a variety of sensory, cognitive, and motor signals. However, the responses of individual neurons often exhibit com...

Separating Cognitive and Motor Processes: A Breakthrough in Mouse Behavioral Research Academic Background In the study of animal behavior, cognitive processes and motor processes are often closely intertwined. For example, when a mouse explores its environment, its facial expressions or active sampling behaviors not only reflect movement but are al...

Exploration of the Architecture of the Human Default Mode Network: A Study Based on Cytoarchitecture, Wiring, and Signal Flow Academic Background The Default Mode Network (DMN) is a set of brain regions that are highly active during resting states, primarily distributed across the frontal, temporal, and parietal lobes. The DMN plays a crucial role ...

Cell-Type Classification of Psychiatric Disorders: New Study Reveals Cellular Basis of Schizophrenia and Other Complex Brain Disorders Academic Background Psychiatric disorders, such as schizophrenia, depression, and bipolar disorder, are significant public health issues worldwide. These disorders are typically caused by a combination of multiple g...