A Distinct Hypothalamus–Habenula Circuit Governs Risk Preference

Study on the Hypothalamus-Habenula Circuit Regulating Risk Preference Academic Background In complex and uncertain environments, animals need to assess risks to make survival-favorable decisions. When faced with safe and risky options, animals usually exhibit a strong preference for one option, which remains consistent over time. However, how this ...

A Large Field-of-View, Single-Cell-Resolution Two- and Three-Photon Microscope for Deep and Wide Imaging

A Large Field-of-View, Single-Cell-Resolution Two- and Three-Photon Microscope for Deep and Wide Imaging

Large field-of-view, single-cell-resolution two- and three-photon microscope for deep and wide imaging Research Background and Problem Statement Multiphoton microscopy (MPM) is a powerful tool for deep tissue imaging, especially in the study of brain function in vivo. However, while traditional two-photon microscopy (2PM) can achieve a larger imagi...

UVC LED System for Prolonging the Postharvest Shelf Life of Murcotts

Academic Background Citrus fruits have long been favored by consumers for their rich nutritional value and unique flavor. However, citrus fruits are highly susceptible to diseases during postharvest storage, particularly green mold caused by Penicillium digitatum. This disease leads to fruit decay and significantly shortens storage life. Traditiona...

Establishing Functionally Segregated Dopaminergic Circuits

Functional Segregation of Dopaminergic Neural Circuits and Their Developmental Mechanisms Academic Background Dopamine is a crucial neurotransmitter in the brain, regulating various physiological functions, including motor control, emotional regulation, motivation, learning, and memory. Dopaminergic neurons are primarily located in the midbrain, an...

Proteomic Analysis Reveals Distinct Cerebrospinal Fluid Signatures Across Genetic Frontotemporal Dementia Subtypes

Academic Background Frontotemporal Dementia (FTD) is a group of progressive neurodegenerative diseases characterized primarily by behavioral changes, language impairment, or motor dysfunction. Although the incidence of FTD is lower than that of Alzheimer’s Disease (AD), it remains one of the leading causes of early-onset dementia. The molecular bas...