Speech Prosody Serves Temporal Prediction of Language via Contextual Entrainment

Medicine, Neurology, Clinical Psychology, Life Sciences, Biophysics,
speech prosody   temporal prediction   contextual entrainment   electrophysiology   MEG   language comprehension  

Time prediction plays an important role in language comprehension, making language processing faster and more efficient. Especially in complex auditory and language processing, predicting the information of the upcoming utterance can improve comprehension efficiency and reduce cognitive load. Existing research has shown that listeners can utilize t...

Gliomatosis cerebri in children: a poor prognostic phenotype of diffuse gliomas with a distinct molecular profile

Medicine, Pediatrics, Medical Laboratory Science, Neurology, Oncology, Life Sciences, Cell Biology, Genetics,
pediatric gliomatosis cerebri   diffuse gliomas   molecular profile   poor prognosis   genetic alterations   high-grade gliomas   brain tumor  

Childhood Gliomatosis Cerebri: A Poor Prognosis Phenotype of Diffuse Glioma with Distinct Molecular Characteristics Introduction Gliomatosis cerebri (GC) is a highly invasive form of diffuse glioma. It was initially discarded as an independent pathological type due to its indeterminate molecular characteristics. However, with the advancements in mo...

Raman-Based Machine Learning Platform Reveals Unique Metabolic Differences Between IDHmut and IDHwt Glioma

Information Science, Artificial Intelligence, Medicine, Medical Laboratory Science, Neurology, Medical Imaging, Oncology, Life Sciences, Cell Biology, Biochemistry,
Raman spectroscopy   glioma   machine learning   FFPE tissue   lipid metabolism  

Study on Metabolic Differences between IDH Mutant and Wild-type Glioma Cells Using Raman Spectroscopy and Machine Learning Platform Background Introduction In the diagnosis and treatment of gliomas, formalin-fixed, paraffin-embedded (FFPE) tissue sections are commonly used. However, due to background noise interference from the embedding medium, th...

Disturbance in Cerebral Blood Microcirculation and Hypoxic-Ischemic Microenvironment are Associated with the Development of Brain Metastasis

Medicine, Neurology, Neurosurgery, Oncology, Life Sciences, Immunology,
cerebral blood microcirculation   hypoxic-ischemic microenvironment   brain metastasis   angiogenesis   ANG-2   VEGF   anti-angiogenic therapy  

Microcirculatory Disorders of Cerebral Blood Flow and the Hypoxic-Ischemic Microenvironment Related to Brain Metastasis Development Background and Research Motivation Brain metastasis (BM) is an increasing challenge in oncology due to its severe impact on neurological function, limited treatment options, and resulting poor prognosis. BM develops th...

Representation of Genomic Intratumor Heterogeneity in Multi-Region Non-Small Cell Lung Cancer Patient-Derived Xenograft Models

Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology, Genetics,
non-small cell lung cancer   xenograft models   tumor heterogeneity   genomic evolution   multi-region sampling  

Manifestations of Genomic-Level Intratumoral Tumor Heterogeneity in Multi-Region Patient-Derived Xenograft Models of Non-Small Cell Lung Cancer Academic Background and Research Motivation Patient-Derived Xenograft (PDX) models are widely used in cancer research. PDX models are established by transplanting human tumors into immunodeficient mice. The...