Association Between Epigenetic Age Acceleration Estimates and Cognitive Trajectories in the Women’s Health Initiative Memory Study Background Maintaining cognitive function is crucial for independent living among older adults. With the growth of the aging population, cognitive decline has become a significant public health challenge. Many studies h...

Metagenomic Next-Generation Sequencing as an Alternative to Procalcitonin in Guiding Antibiotic Use in Patients with Acute Necrotizing Pancreatitis and Fever Background and Research Objectives Acute pancreatitis (AP) is one of the leading causes of emergency hospital admissions for digestive system diseases, with significant medical resource utiliz...

Precise and Safe Lung Segmentectomy Enabled by Dual-Channel Near-Infrared Fluorescence Tumor and Pleural Demarcation Lung cancer is a leading cause of cancer-related deaths globally. Since the introduction of computed tomography screening, the early detection rate of lung cancer has greatly increased, significantly reducing mortality rates. Studies...

Transforming the Operating Room into a Mixed Reality Environment: A Prospective Clinical Study on Aneurysm Clipping The surgical treatment of cerebral aneurysms is a highly complex and delicate process in neurosurgery. Researchers continue to explore new technologies and methods to improve surgical outcomes. In recent years, the development of Mixe...

The SIRT1-Rab7 Axis Regulates NLRP3 and STING Activation in Sepsis-Induced Acute Lung Injury via Terminal Endosome-Dependent Mitophagy Academic Background Acute lung injury (ALI) is one of the leading causes of death in septic patients, primarily due to the pro-inflammatory changes and permeability defects in endothelial cells (ECs). Mitochondrial ...