Trimming Helicoidal: A Soft Structure with High Precision, Large Workspace, and Compliant Interaction Background Introduction In recent years, inspired by biological systems, many researchers have gradually shifted from traditional rigid robot paradigms towards designs that incorporate compliant materials and structures. An elephant trunk is a typi...

Accelerating the Discovery of Ionizable Lipids for mRNA Delivery using Machine Learning and Combinatorial Chemistry Research Background To fully realize the potential of mRNA therapies, it is essential to expand the toolkit of lipid nanoparticles (LNPs). However, a key bottleneck in LNP development is identifying new ionizable lipids. Previous stud...

Report on the Study of Quantum Coherent Spins in Hexagonal Boron Nitride at Room Temperature Introduction The realization of quantum networks and sensors requires solid-state spin-photon interfaces that possess single-photon emission capabilities and long-lived spin coherence, which can be integrated into scalable devices. Ideally, these devices sh...

Study on Chirality Transfer in Liquid Crystal Viruses Chirality is a phenomenon commonly found in nature and holds significant influence in various fields such as biology, chemistry, physics, and materials science. However, the mechanism of chirality transfer from nanoscale building blocks to macroscopic helical structures remains an unsolved myste...

Unique Patterns of Glycosylation in Plaques and Microglia in Alzheimer’s Disease Research Background Alzheimer’s disease (AD) is the most common form of dementia and a devastating neurodegenerative disorder. AD is characterized by two pathological features: extracellular β-amyloid (Aβ) plaques and intracellular phosphorylated Tau neurofibrillary ta...