The purpose of this paper is to explore the developmental origin, biological characteristics, and association with eye diseases of tissue-resident macrophages in the field of ophthalmology—hyalocytes. The eye is a highly specialized sensory organ that contains the retina, part of the central nervous system, as well as non-neuronal parts like the tr...

Morphology-Specific Calcium Signaling Characteristics in Human Microglia Background and Research Objectives Microglia are the primary immune cells of the central nervous system (CNS), involved in almost all physiological and pathological processes, including development, synaptic transmission, neuroplasticity, sleep, trauma, glioblastoma, and neuro...

Key Mediator Akap8l in Microglia for Diabetes-Associated Cognitive Impairment: Functions via Autophagy Inhibition and Neuroinflammation Academic Background In recent years, diabetes-associated cognitive impairment (DACI) has received increasing attention. It not only poses a threat to the self-management capabilities of diabetic patients but also i...

Neuroinflammation and Epilepsy: The Role of Inflammasomes in Traumatic Brain Injury Background and Purpose Traumatic Brain Injury (TBI) refers to changes in brain function and pathology resulting from physical trauma to the head or neck. Apart from common behavioral and psychological disorders, post-traumatic epilepsy (PTE) is one of the most sever...

Research on Saturated Fatty Acids and Brain Function Background Introduction Obesity and metabolic syndrome are major global health challenges today. Numerous studies have shown that excessive consumption of diets rich in saturated fats leads to obesity, accompanied by a series of metabolic complications such as insulin resistance and diabetes. How...