TDRD3 Deficient Mice Exhibit Deficits in Neurogenesis and Synaptic Plasticity at Both Post-transcriptional and Behavioral Levels Research Background Topoisomerase 3b (top3b) is a dual-activity topoisomerase capable of resolving DNA and RNA topological problems. An increasing body of evidence indicates that top3b functions as a conserved complex wit...

One of the key issues in understanding the visual system’s selective attention is how it optimizes the perception and processing of visual information in specific behavioral contexts. Although previous research has analyzed the pivotal role of individual neuron firing rates in information transmission, our understanding remains limited regarding ho...

ABHD6 Drives Endocytosis of AMPA Receptors to Regulate Synaptic Plasticity and Learning Flexibility Research Background In the exploration of the neural system’s mechanisms, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors (AMPAR) maintain the tuning ability of neurons in both resting and active states through the regulation of...

Academic Report on “Contralateral Delay Activity and Alpha Lateralization Reflect Retinotopic and Screen-Centered Reference Frames in Visual Memory” Introduction The visual system is organized in a lateralized manner, with the left and right visual fields processed by the contralateral cerebral cortex. This organization applies not only to percepti...

Mesoscale Organization of Ventral and Dorsal Visual Pathways in Macaque Monkey Revealed by 7T fMRI In the journal Progress in Neurobiology, a research team from the Interdisciplinary Institute of Neuroscience and Technology and the Department of Neurosurgery at the Second Hospital in Zhejiang University published a paper titled “Mesoscale organizat...

Analyzing the Gene Expression Network in Developing Hippocampus from the Perspective of NEIL3 Deficiency Background The hippocampus, a crucial region of the brain, is well-regarded for its key roles in memory consolidation, information processing, and emotional regulation. In the field of neuroscience research, the gene regulatory mechanisms of the...