Regulation of L-type Calcium Channels in Low-Intensity Pulsed Ultrasound (LIPUS) Excitation of Cultured Hippocampal Neurons Background In recent years, ultrasound stimulation has been widely used as a non-invasive technique to regulate neuronal activity both in vivo and in vitro. However, the potential mechanism of neural modulation effects induced...

Mechanism Study of High Magnesium Promoting Binocular Vision Recovery in Amblyopia Patients: The Role of TRPM7 Abnormal visual experiences during critical periods of brain development can lead to visual function deficits, such as amblyopia. Current research suggests that high magnesium (Mg^2+) supplementation can restore synaptic plasticity in the ...

Contemporary Anesthesia Safety Research: New Pathological Mechanism of Fine Motor Deficits in Mice With the advancement of modern anesthesia techniques, millions of lives rely on successful surgeries each year. However, various clinical studies, including those by the Mayo Anesthesia Safety in Kids (MASK) group, suggest that children who undergo mu...

Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Project to Bed Nucleus of the Stria Terminalis to Regulate Wakefulness and Positive Emotional States Background The nucleus accumbens (NAc) plays a crucial role in regulating motivation, reward, and many behaviors that depend on high levels of arousal. However, research on the neural mechani...

In the latest research paper “Chemokine CCL2 Promotes Excitatory Synaptic Transmission in Hippocampal Neurons via GluA1 Subunit Trafficking” published in “Neurosci. Bull.”, researchers from multiple institutions, including the Shanghai Institute of Neuroscience, Chinese Academy of Sciences, and the School of Life Sciences, Peking University, have d...

Study on Myosin Va-dependent NMDA Receptor Transport Mechanism in Hippocampal Neurons In hippocampal neurons, NMDA receptors (N-Methyl-D-Aspartate Receptor, abbreviated as NMDAR) are a subtype of glutamate receptors, crucial for regulating postsynaptic responses and various brain functions. The number of NMDARs in the postsynaptic region can change...