The Key Role of RELMβ in Food Allergy Academic Background Food allergy (FA) is a common immune system disorder, particularly prevalent among children. The occurrence of food allergy is associated with abnormal immune responses to food antigens, especially the dysregulation of type 2 immune responses. Type 2 immune responses are typically defense me...

Research on the Functional Mapping of Rubisco Enzyme Background Introduction Rubisco (ribulose-1,5-bisphosphate carboxylase/oxygenase) is the most abundant enzyme on Earth, responsible for the carbon dioxide fixation process in photosynthesis. However, Rubisco’s catalytic efficiency is low, and it is prone to side reactions with oxygen, limiting th...

Mitochondrial Transfer and Immune Evasion Mechanisms in the Tumor Microenvironment Academic Background Tumor cells evade immune system attacks, particularly by T cells, through various mechanisms in the Tumor Microenvironment (TME). Although Immune Checkpoint Inhibitors (ICIs) have achieved significant progress in the treatment of various cancers, ...

Complete Human Recombination Maps Academic Background In genetic research, recombination is one of the key mechanisms by which organisms generate genetic diversity. Recombination not only affects the transmission and combination of genes but also plays a crucial role in natural selection and population history inference. However, existing recombina...

Precise Modeling of Mitochondrial Diseases: Research Based on Optimized Mitobes Academic Background Mitochondrial diseases are a group of genetic disorders caused by mutations in mitochondrial DNA (mtDNA), which affect cellular energy metabolism and lead to dysfunction in multiple organs. Mitochondrial DNA mutations can be homoplasmic (affecting al...