3D Bioprinting of a Dermal Scaffold for Full-Thickness Skin Tissue Regeneration

3D Bioprinting of Dermal Scaffolds for Full-Thickness Skin Tissue Regeneration Academic Background The skin, being the largest organ of the human body, plays a crucial role in defending against external environmental damage and preventing microbial invasion. However, when the skin suffers extensive damage, its self-repair capabilities are limited, ...

Enhancing Angiogenesis and Osseointegration through a Double Gyroid Ti6Al4V Scaffold with Triply Periodic Minimal Surface

Application of Double Gyroid Titanium Alloy Scaffolds Based on Triply Periodic Minimal Surface Structures in Bone Repair Academic Background Bone defect repair is a significant challenge in the field of orthopedics, especially in cases of critical-size bone defects caused by trauma, tumors, inflammation, and other diseases. Currently, the commonly ...

Magnesium and Gallium-Co-loaded Microspheres Accelerate Bone Repair via Osteogenesis and Antibiosis

Research on Magnesium and Gallium Co-loaded Microspheres Accelerating Bone Repair Academic Background Bone defects are a common clinical challenge, often caused by infection, tumor resection, or mechanical trauma. Bone defects not only affect patients’ quality of life but may also lead to functional loss. Although bone grafting is currently the pri...

Novel Heart Valve Leaflet Designs with Stiff Polymeric Materials and Biomimetic Kinematics

Novel Heart Valve Leaflet Design: Research Based on High-Stiffness Polymeric Materials and Biomimetic Kinematics Academic Background Heart valve disease is a significant global health issue, with over 850,000 patients requiring heart valve replacement surgery annually. Currently, the heart valves used in clinical practice are mainly divided into tw...

Cav3.3-Mediated Endochondral Ossification in a Three-Dimensional Bioprinted GelMA Hydrogel

Cav3.3-Mediated Endochondral Ossification in a Three-Dimensional Bioprinted GelMA Hydrogel

Study on Cav3.3-Mediated Endochondral Ossification in 3D Bioprinted GelMA Hydrogel Research Background Bone development is a complex process, in which the growth plate (GP) plays a crucial role in the longitudinal growth of long bones. The growth plate regulates bone maturation through the process of endochondral ossification (EO). However, GP dysf...