The Role of Cystatin F in Regulating Neuroinflammation and Demyelination in Spinal Cord Poliovirus Infection Background Knowledge Cystatin F is a secreted lysosomal cysteine protease inhibitor associated with every stage of virus-related neurological diseases, including host defense, demyelination, and myelination. However, research on how Cystatin...

The Therapeutic Role of IFN-γ in Experimental Autoimmune Encephalomyelitis is Mediated by Tolerogenic Subsets of Splenic CD11b+ Myeloid Cells Research Background Multiple sclerosis (MS) is a chronic autoimmune disease characterized by demyelination and axonal damage in the central nervous system (CNS). Although the etiology of MS is unclear, both g...

Review of Research on the Treatment Potential for Cognitive Deficits in Traumatic Brain Injury Research Background Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. In Europe, the annual incidence of TBI is at least 4 million cases, imposing a heavy burden on patients, society, and health systems, yet the available ...

Study on the Differential Effects of Blood Flow Restriction Training on Strength Gains and Precise Force Control Research Background Blood Flow Restriction (BFR) training, an emerging method for enhancing muscle strength, has garnered attention from researchers and clinical medicine in recent years. BFR training with low-load resistance exercise en...

Neonatal Respiratory Infections Lead to Brainstem Neuroinflammation Introduction Respiratory infections are one of the most common diseases and causes of morbidity among newborns. During the acute phase, infections are known to cause widespread peripheral inflammation. However, the effect of this inflammation on the critical neural centers that con...