A Dual-Pipeline Lactate Removal Strategy to Reverse Vascular Hyperpermeability for the Management of Lipopolysaccharide-Induced Sepsis

Chemistry, Nanoscience, Medicinal Chemistry, Medicine, Infectious Diseases, Basic Medical Sciences, Life Sciences, Biochemistry, Bioengineering, Immunology,
lactate removal   vascular hyperpermeability   sepsis   lipopolysaccharides   nanohybrids   inflammatory response   endothelial barrier function  

A Novel Dual-Pipeline Lactate Removal Strategy for Sepsis Treatment Background Sepsis, defined as multi-organ dysfunction caused by a dysregulated host immune response to bloodborne infection, remains a severe global public health issue. Despite advances in modern medicine, the diagnosis and treatment of sepsis pose significant challenges. Statisti...

Bioprinted Micro-Clots for Kinetic Analysis of Endothelial Cell-Mediated Fibrinolysis

Medicine, Medical Laboratory Science, Hematology, Pharmacy, Cardiovascular System, Life Sciences, Cell Biology, Biochemistry, Bioengineering, Immunology, Biophysics,
bioprinting   micro-clots   fibrinolysis   endothelial cells   venous thromboembolism   drug testing   high-throughput analysis  

Breakthrough Research on Micro-Scale Exploration of Thrombolysis Kinetics Research Background and Problem Venous thromboembolism (VTE), a severe health condition, causes approximately 500,000 deaths annually in the United States alone. The occurrence of VTE is closely related to the formation and resistance to dissolution of thrombi in veins, commo...

Incorporating Bone-Derived ECM into Macroporous Microribbon Scaffolds to Accelerate Bone Regeneration

Medicine, Orthopedics, Life Sciences, Cell Biology, Bioengineering, Immunology,
bone regeneration   macroporous scaffolds   extracellular matrix   tissue engineering   immunomodulation  

Incorporating Bone-Derived Extracellular Matrix (Bone-Derived ECM) into Macroporous Microribbon Scaffolds Accelerates Bone Regeneration Research Report With the continuous progress in the biomedical field, the application of tissue engineering and regenerative medicine in various tissue repairs has become increasingly important. However, research o...

New Advances in Periodontal Functional Materials Based on Antibacterial, Anti-inflammatory, and Tissue Regeneration Strategies

Chemistry, Nanoscience, Polymer Chemistry, Medicinal Chemistry, Medicine, Oral Sciences, Life Sciences, Biochemistry, Bioengineering, Immunology, Microbiology,
periodontitis   antibacterial materials   anti-inflammatory therapy   tissue regeneration   multifunctional materials   biomaterials   innovative treatment  

A Review on Novel Periodontal Functional Materials: Comprehensive Exploration of Antibacterial, Anti-inflammatory, and Tissue Regeneration Strategies Academic Background and Research Significance With the accelerating trend of global population aging, the concern for oral health issues is increasing. Periodontitis, as a common bacterial infectious ...

Enhancing Immunomodulation and Osseointegration of Bone Implants via Thrombin-Activated Platelet-Rich Plasma Self-Assembly

Chemistry, Medicinal Chemistry, Medicine, Orthopedics, Life Sciences, Biochemistry, Bioengineering, Immunology,
bone implants   thrombin   platelet-rich plasma   immunomodulation   osseointegration   self-assembly   tissue repair  

Enhancing Immunomodulation and Osseointegration of Bone Implants: A Detailed Overview of Thrombin-Activated Platelet-Rich Plasma (PRP) Self-Assembly Technology Background Introduction To address the challenge of bone defect repair, bone implants play a critical role in modern medicine. However, existing bone implant materials like Polyetheretherket...