The Role of Radioresistant-Related Telomere Genes in the Prognosis and Immune Infiltration of Lung Adenocarcinoma

Medicine, Respiratory System, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology, Genetics,
lung adenocarcinoma   radiotherapy   telomere genes   immune infiltration   prognostic model  

The Impact of Radioresistant-Related Telomere Genes on Prognosis and Immune Infiltration in Lung Adenocarcinoma Lung adenocarcinoma (LUAD), a common subtype of non-small cell lung cancer (NSCLC), has a high incidence and mortality rate. Despite significant progress in early detection and treatment, the overall survival (OS) rate of LUAD patients re...

Multiomic Analysis Identifies Survival Predictors in African American Patients with Acute Myeloid Leukemia

Medicine, Medical Laboratory Science, Hematology, Oncology, Life Sciences, Cell Biology, Immunology, Genetics,
acute myeloid leukemia   African American   gene mutations   inflammation   survival predictors   genomic analysis   multiomic study  

Multi-omics Analysis Reveals Predictors of Survival in African American AML Patients Background and Objectives Acute Myeloid Leukemia (AML) is a hematologic malignancy characterized by clonal expansion of myeloid progenitor cells driven by genomic alterations. Despite advances in genomic profiling, studies focusing on diverse ancestral populations ...

Effectiveness of Ocrelizumab in Primary Progressive Multiple Sclerosis: A Multicenter, Retrospective Real-World Study

Medicine, Rheumatology and Immunology, Environmental and Public Health, Basic Medical Sciences, Neurology, Life Sciences, Immunology,
Ocrelizumab   Primary Progressive Multiple Sclerosis   Efficacy   Multicenter Study   Real-World  

Effectiveness of Ocrelizumab in Primary Progressive Multiple Sclerosis: A Multicenter, Retrospective Real-World Study Background and Research Motivation Multiple sclerosis (MS) is a chronic, complex, inflammatory, and degenerative demyelinating disease primarily affecting the central nervous system (CNS). It can lead to neurological impairments in ...

Assessing Sustained B-Cell Depletion and Disease Activity in a French Multiple Sclerosis Cohort Treated by Long-Term IV Anti-CD20 Antibody Therapy

Medicine, Infectious Diseases, Neurology, Medical Imaging, Life Sciences, Biochemistry, Immunology,
multiple sclerosis   anti-CD20   B-cell depletion   disease activity   long-term therapy   adverse events   immunotherapy  

Long-term Intravenous Anti-CD20 Antibody Therapy Assessment in a French Multiple Sclerosis Cohort Background and Research Motivation Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease affecting the central nervous system, leading to varying degrees of physical and cognitive impairment. Recent Phase II and III clinical trials of...

Optimized Nutrition in Mitochondrial Disease Correlates to Improved Muscle Fatigue, Strength, and Quality of Life

Medicine, Basic Medical Sciences, Medical Laboratory Science, Neurology, Gastroenterology, Life Sciences, Biochemistry, Immunology,
mitochondrial disease   nutritional status   muscle fatigue   quality of life   macronutrients   inadequate calorie intake   nutritional intervention  

Optimized Nutritional Interventions Improve Muscle Fatigue, Strength, and Quality of Life in Patients with Primary Mitochondrial Disease Background Introduction Primary mitochondrial disease (PMD) encompasses a group of disorders caused by mutations in mitochondrial DNA or nuclear DNA, affecting systemic energy metabolism. The prevalence is approxi...

Wavelet-Based Bracketing, Time–Frequency Beta Burst Detection: New Insights in Parkinson's Disease

Medicine, Basic Medical Sciences, Neurology, Medical Imaging, Life Sciences, Immunology, Biophysics,
Parkinson's disease   beta oscillations   low beta   high beta   closed-loop control   neuromodulation   signal processing  

Parkinson’s Disease Research Report: Beta Burst Behavior Analysis Using a Wavelet-Based Time-Frequency Detection Framework Background Parkinson’s disease (PD) is a prevalent neurodegenerative disorder characterized by motor dysfunction, including tremors, rigidity, and bradykinesia. Recent studies have linked motor impairments in PD to excessive sy...