Hemispheric Asymmetry of Intracortical Myelin Orientation in the Mouse Auditory Cortex

Hemispheric Asymmetry of Myelin Orientation in the Mouse Auditory Cortex Academic Background The mammalian brain exhibits inherent asymmetry, which is particularly evident in the motor system and acoustic communication. For example, both mice and humans show hemispheric differences in auditory processing. This asymmetric organization allows the bra...

Pallidal Spike-Train Variability and Randomness are the Most Important Signatures to Classify Parkinson's Disease and Cervical Dystonia

Classification Study of Parkinson’s Disease and Cervical Dystonia Academic Background Parkinson’s Disease (PD) and Cervical Dystonia (CD) are two common movement disorders whose pathological mechanisms are closely related to abnormal neuronal activity in the basal ganglia. The basal ganglia are a crucial brain structure for motor control, with the ...

Postcolitis Alterations in Dose-Dependent Effects of 5-HT1A Agonist Buspirone on Nociceptive Activity of the Raphe Magnus and Dorsal Raphe Neurons in Rats

The Role of 5-HT1A Agonist Buspirone in Pain Regulation in Postcolitis Rats Background In recent years, increasing clinical and experimental evidence has shown that the brain’s serotonin (5-HT) system plays a significant role in the pathogenesis of gastrointestinal disorders, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IB...

Synaptic Targets and Cellular Sources of CB1 Cannabinoid Receptor and Vesicular Glutamate Transporter-3 Expressing Nerve Terminals in Relation to GABAergic Neurons in the Human Cerebral Cortex

Distribution and Function of CB1 Cannabinoid Receptor and VGLUT3 in the Human Cerebral Cortex Background Cannabinoid receptor 1 (CB1) regulates synaptic transmission through presynaptic receptors in nerve terminals, and its physiological roles are of significant clinical relevance. However, the cellular sources and synaptic targets of CB1-expressin...

Effects of Altered Haptic Feedback Gain Upon Balance Are Explained by Sensory Conflict Estimation

Effects of Altered Haptic Feedback Gain on Balance and Its Neural Mechanisms Background In daily life, human balance control relies on multiple sensory inputs, including vision, vestibular sensation, and proprioception. Haptic feedback also plays a crucial role in balance control, especially when touching a fixed object, as it significantly reduces...