Academic Background Bioluminescence technology is a highly sensitive and non-invasive imaging technique, enabling real-time monitoring in living organisms without the need for external light sources. Luciferase is the key enzyme that catalyzes the light-emitting reaction, but natural luciferases face multiple limitations, such as poor protein foldi...

Academic Background In the field of solar energy conversion, molecular catalysts have attracted significant attention due to their high activity and structural tunability. However, most molecular catalysts operate under homogeneous conditions, which are not favorable for large-scale and recyclable utilization. Therefore, immobilizing molecular cata...

Background Introduction The application of live bacteria in the biomedical field has garnered significant attention in recent years. Traditionally, bacteria were viewed as pathogens that needed to be eradicated. However, with the advancement of modern bacteriology, there has been a growing recognition of the complex symbiotic relationship between b...

Academic Background Hereditary deafness is one of the most common sensory disorders worldwide, affecting over 400 million people, with approximately 60% of congenital deafness linked to genetic factors. Although adeno-associated virus (AAV)-mediated gene therapy shows great potential in treating hereditary deafness, significant concerns remain rega...

Dynorphin is an endogenous opioid peptide that primarily acts through κ-opioid receptors (KOR) and is widely involved in the regulation of various behaviors, including reward and aversive responses. However, the specific mechanisms of Dynorphin/KOR signaling in reward-seeking behaviors remain unclear. Previous research has predominantly focused on ...