Recommendations for Implementing the HEvolution Alliance for Aging Biomarkers Initiative

Medicine, Geriatrics, Life Sciences, Cell Biology, Biochemistry, Bioengineering, Immunology, Genetics,
aging biomarkers   health expectancy   geroscience   biological age   longitudinal studies  

Promoting Healthy Longevity: Implementation Recommendations for the Hevolution Alliance for Aging Biomarkers Initiative Academic Background and Research Motivation With the intensification of global population aging, human life expectancy has significantly increased, but the growth in healthy life expectancy (i.e., years lived in good health) has b...

A Practical Micropipette-Image Calibration Method for Somatic Cell Microinjection

Information Science, Automation, Life Sciences, Cell Biology,
micropipette calibration   somatic cell microinjection   automation technology   micromanipulation   image processing  

Micropipette-Image Calibration Method Based on Micromanipulation System for Somatic Cell Microinjection Research Background Microinjection is a technique that employs a fine micropipette to inject a precise amount of genetic material, drugs, or other exogenous substances directly into cells or tissues. This technology plays a pivotal role in biomed...

Single-Cell Transcriptomic Profiling of Heart Reveals ANGPTL4 Linking Fibroblasts and Angiogenesis in Heart Failure with Preserved Ejection Fraction

Medicine, Cardiovascular System, Life Sciences, Cell Biology,
heart failure   single-cell sequencing   ANGPTL4   metabolism   angiogenesis  

Single-Cell Transcriptomics Reveals the Relationship Between Cardiac Fibroblasts and Angiogenesis: The Key Role of ANGPTL4 in HFpEF Background Introduction Heart failure is one of the major global health challenges today. Heart failure is categorized into heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection...

Identification of a Transcription Factor Aomsn2 of the HOG1 Signaling Pathway Contributes to Fungal Growth, Development and Pathogenicity in Arthrobotrys oligospora

Medicine, Life Sciences, Cell Biology, Biochemistry, Microbiology,
fungus   transcription factor   HOG1 signaling pathway   growth   pathogenicity  

The Role of Transcription Factor AoMsn2 in the Hog1 Signaling Pathway in Fungal Growth, Development, and Pathogenicity Background Plant-parasitic nematodes cause significant annual losses to agriculture, while nematode-trapping fungi (NT fungi), due to their ability to capture nematodes by forming specialized trapping structures, have gradually bec...

Exploring the Impacts of Senescence on Implantation and Early Embryonic Development

Medicine, Obstetrics and Gynecology, Life Sciences, Cell Biology,
senescence   implantation   early embryonic development   scientific paper   research  

Exploring the Impacts of Senescence on Implantation and Early Embryonic Development Using Totipotent Cell-Derived Blastoids Academic Background With the increasing trend of delayed childbearing in modern society, reproductive issues among women of advanced maternal age (AMA) have become increasingly prominent. Studies have shown that the implantati...

Unlocking Melanoma Suppression: Insights from Plasma-Induced Potent miRNAs through PI3K-AKT-ZEB1 Axis

Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
Non-thermal plasma   miRNA sequencing   Differential regulation   Melanoma inhibition   PI3K-AKT-ZEB1 axis  

Study on Melanoma Suppression by Non-Thermal Atmospheric Pressure Plasma via the PI3K-AKT-ZEB1 Axis Academic Background Melanoma is the most aggressive and deadly form of skin cancer, particularly in its advanced stages, making treatment extremely challenging. Although recent advancements in targeted therapy and immunotherapy have improved patient ...