Bacterial Toxins Induce Non-Canonical Migracytosis to Aggravate Acute Inflammation

Report on the Study of Bacterial Toxins Inducing Non-Canonical Migracytosis and Aggravating Acute Inflammation Background and Research Objectives In recent years, the discovery of migrasomes, a new type of membrane structure, has gained significant attention in the scientific community for its role in cell migration and various biological functions...

Prehospital Lactate Levels Obtained in the Ambulance and Prediction of 2-Day In-Hospital Mortality in Patients with Traumatic Brain Injury

Research Report Background Overview Traumatic Brain Injury (TBI) is one of the leading causes of permanent disability and death worldwide. These disorders are dynamic and evolving, involving progressive brain injury and pathophysiological changes accompanied by multi-system damage. The severity of TBI is typically assessed using the Glasgow Coma Sc...

circPTP4A2 Promotes Microglia Polarization in Cerebral Ischemic Stroke via miR-20b-5p/YTHDF1/TIMP2 Axis

Academic Report on the Scientific Paper “circPTP4A2 Promotes Microglial Polarization in Ischemic Stroke via the miR-20b-5p/YTHDF1/TIMP2 Axis” Background Introduction Ischemic stroke (IS) is brain tissue necrosis caused by cerebral blood flow obstruction and is the second leading cause of disability and death globally. Current clinical treatment str...

Brain-Derived Exosomal circRNAs in Plasma Serve as Diagnostic Biomarkers for Acute Ischemic Stroke

Brain-Derived Exosomal Circular RNAs in Plasma as Diagnostic Biomarkers for Acute Ischemic Stroke Acute ischemic stroke (AIS), commonly known as stroke, is a serious condition characterized by interrupted blood flow to the brain, resulting in tissue damage and neurological deficits. Early diagnosis is crucial for effective intervention and manageme...

Association between Time to Treatment with Endovascular Thrombectomy and Home-Time after Acute Ischemic Stroke

The Relationship between Treatment Speed of Endovascular Thrombectomy (EVT) for Acute Ischemic Stroke and Patient’s “Time at Home” Stroke is an acute disease with high disability and mortality rates. However, in recent years, the treatment efficacy of acute ischemic stroke has improved significantly with the development of endovascular thrombectomy...