Sex-dependent effects of carbohydrate source and quantity on caspase-1 activity in the mouse central nervous system

The Gender-Dependent Effects of Carbohydrate Sources and Quantity on Caspase-1 Activity in the Central Nervous System of Mice Research Background With the global intensification of aging, the incidence of cognitive impairments and dementia is rapidly increasing, with Alzheimer’s disease being the most common form of senile dementia. Studies have sh...

Hourly Step Recommendations to Achieve Daily Goals for Working and Older Adults

Timed Step Recommendations to Assist in Achieving Daily Goals - A New Strategy for Working and Elderly Adult Populations With the popularization of health trackers, high-resolution health data (such as hourly step counts) can be collected and used to evaluate health promotion plans. Take daily step goals for example. Research has found that the acc...

Simulation Study Suggests Masks Can Become More Effective When Fewer People Wear Them

The Relationship Between Mask Effectiveness and Population Coverage Rates Background and Research Motivation During the COVID-19 pandemic, non-pharmaceutical interventions (NPIs) such as social distancing, mask-wearing, and test-trace-isolate strategies were widely applied to control the spread of the virus. Despite a large body of empirical resear...

Seeing an Apocalyptic Post-Antibiotic Future Lowers Antibiotics Expectations and Requests

How to Reduce the Expectations and Demand for Antibiotics in the Face of the Threat of a “Post-Antibiotic Era” Introduction Antibiotic resistance is becoming a global public health threat. Although the evolution of this resistance is a biological process, human behavior, especially unnecessary antibiotic use in agricultural production and human med...

Using Large Language Models to Assess Public Perceptions Around Glucagon-Like Peptide-1 Receptor Agonists on Social Media

In the global context, the prevalence of obesity is on the rise, bringing significant impacts to public health. Obesity is independently associated with the incidence and mortality of cardiovascular diseases, with an estimated economic burden exceeding $200 billion annually for healthcare systems. In recent years, glucagon-like peptide-1 (GLP-1) re...