Facile Fabrication of Injectable Multifunctional Hydrogels Based on Gallium-Polyphenol Networks with Superior Antibacterial Activity for Promoting Infected Wound Healing

Chemistry, Nanoscience, Inorganic Chemistry, Polymer Chemistry, Medicine, Infectious Diseases, Rheumatology and Immunology, Pharmacy, Life Sciences, Biochemistry, Bioengineering, Immunology,
Infected wounds   Hydrogels   Polyphenols   Gallium ions   Antibacterial activity   Antibiotic-resistant pathogens   Wound healing  

A Novel Study on Multifunctional Hydrogels for Promoting Infected Wound Healing In the current clinical setting, infected wounds, especially those caused by antibiotic-resistant pathogens, have become a major challenge. These chronic or hard-to-heal wounds often suffer from delayed healing processes due to excessive inflammation, bacterial biofilm ...

A Potential 3-in-1 Combined Anti-SARS-CoV-2 Therapy Using Pulmonary MIL-100(Fe) Formulation

Chemistry, Nanoscience, Medicinal Chemistry, Medicine, Infectious Diseases, Respiratory System, Pharmacy, Life Sciences, Biochemistry, Immunology,
COVID-19   metal-organic frameworks   antiviral therapy   pulmonary treatment   Favipiravir   heparin   drug delivery  

Exploration of a Novel Pulmonary Anti-SARS-CoV-2 Therapy Based on MIL-100(Fe) In recent years, global public health has faced numerous severe challenges, particularly since 2019 with the outbreak of the SARS-CoV-2 coronavirus pandemic. The high transmission rate and persistence of the virus have exposed bottlenecks in current prevention and treatme...

A Dual-Pipeline Lactate Removal Strategy to Reverse Vascular Hyperpermeability for the Management of Lipopolysaccharide-Induced Sepsis

Chemistry, Nanoscience, Medicinal Chemistry, Medicine, Infectious Diseases, Basic Medical Sciences, Life Sciences, Biochemistry, Bioengineering, Immunology,
lactate removal   vascular hyperpermeability   sepsis   lipopolysaccharides   nanohybrids   inflammatory response   endothelial barrier function  

A Novel Dual-Pipeline Lactate Removal Strategy for Sepsis Treatment Background Sepsis, defined as multi-organ dysfunction caused by a dysregulated host immune response to bloodborne infection, remains a severe global public health issue. Despite advances in modern medicine, the diagnosis and treatment of sepsis pose significant challenges. Statisti...

Bioprinted Micro-Clots for Kinetic Analysis of Endothelial Cell-Mediated Fibrinolysis

Medicine, Medical Laboratory Science, Hematology, Pharmacy, Cardiovascular System, Life Sciences, Cell Biology, Biochemistry, Bioengineering, Immunology, Biophysics,
bioprinting   micro-clots   fibrinolysis   endothelial cells   venous thromboembolism   drug testing   high-throughput analysis  

Breakthrough Research on Micro-Scale Exploration of Thrombolysis Kinetics Research Background and Problem Venous thromboembolism (VTE), a severe health condition, causes approximately 500,000 deaths annually in the United States alone. The occurrence of VTE is closely related to the formation and resistance to dissolution of thrombi in veins, commo...

New Advances in Periodontal Functional Materials Based on Antibacterial, Anti-inflammatory, and Tissue Regeneration Strategies

Chemistry, Nanoscience, Polymer Chemistry, Medicinal Chemistry, Medicine, Oral Sciences, Life Sciences, Biochemistry, Bioengineering, Immunology, Microbiology,
periodontitis   antibacterial materials   anti-inflammatory therapy   tissue regeneration   multifunctional materials   biomaterials   innovative treatment  

A Review on Novel Periodontal Functional Materials: Comprehensive Exploration of Antibacterial, Anti-inflammatory, and Tissue Regeneration Strategies Academic Background and Research Significance With the accelerating trend of global population aging, the concern for oral health issues is increasing. Periodontitis, as a common bacterial infectious ...

Enhancing Immunomodulation and Osseointegration of Bone Implants via Thrombin-Activated Platelet-Rich Plasma Self-Assembly

Chemistry, Medicinal Chemistry, Medicine, Orthopedics, Life Sciences, Biochemistry, Bioengineering, Immunology,
bone implants   thrombin   platelet-rich plasma   immunomodulation   osseointegration   self-assembly   tissue repair  

Enhancing Immunomodulation and Osseointegration of Bone Implants: A Detailed Overview of Thrombin-Activated Platelet-Rich Plasma (PRP) Self-Assembly Technology Background Introduction To address the challenge of bone defect repair, bone implants play a critical role in modern medicine. However, existing bone implant materials like Polyetheretherket...