Traumatic Experiences, Dissociative Symptoms, and Alexithymia in Patients with Alopecia Areata

Traumatic Experiences, Dissociative Symptoms, and Alexithymia in Patients with Alopecia Areata Academic Background Alopecia Areata (AA) is an inflammatory autoimmune disease targeting hair follicles, with its exact etiology remaining unclear. Studies suggest that genetic, environmental, autoimmune, and psychological factors may play significant rol...

Experience-Dependent Dopamine Modulation of Male Aggression

Experience-Dependent Dopamine Modulation of Male Aggression in Mice Academic Background Aggression is a common social behavior in the animal kingdom, crucial for territory defense, resource competition, and mate protection. Although the role of dopamine in regulating aggression has been extensively studied, its specific neural mechanisms remain unc...

Genomics Yields Biological and Phenotypic Insights into Bipolar Disorder

Genomic Research on Bipolar Disorder Background Introduction Bipolar Disorder (BD) is a severe mental illness that significantly contributes to the global disease burden. Despite its high heritability (60-80%), the majority of its genetic basis remains unclear. Previous studies have primarily focused on European populations, with limited exploratio...

Living in Biological Darkness II: Impact of Winter Habitual Daytime Light on Night-time Sleep

The Impact of Winter Urban Light on Night-Time Sleep Background Light and darkness are the primary environmental factors regulating human circadian rhythms. In natural environments, humans are exposed to light levels ranging from 3,000 lux (cloudy winter sky) to 100,000 lux (clear sky). However, in modern urban environments, especially during winte...

Laser-Induced Olfactory Bulbectomy in Adult Zebrafish as a Novel Putative Model for Affective Syndrome: A Research Tribute to Brian Leonard

Study on Laser-Induced Olfactory Bulbectomy in Zebrafish as a Novel Model for Affective Syndrome Background Affective disorders, such as depression, are common mental health issues worldwide. Although rodent models have played a significant role in depression research, their cross-species applicability has limitations. Zebrafish (Danio rerio), as a...