Single-Cell and Spatially Resolved Interactomics of Tooth-Associated Keratinocytes: Exploring the Role of Structural Immunity in Periodontitis Background Periodontitis is a chronic inflammatory disease that affects the periodontal tissues and impacts billions of people globally, potentially resulting in tooth loss. It is primarily caused by polybac...

Identification of Nanaomycin A and Its Analogs as Functional Inhibitors of the Type IX Secretion System in Porphyromonas gingivalis Using a Novel Screening Method Academic Background Porphyromonas gingivalis is a Gram-negative anaerobic bacterium recognized as one of the primary pathogens in chronic periodontitis. Beyond periodontal diseases, P. gi...

Application of LBL Coatings in the Treatment of Dental Implant-Related Infections Background Dental implant-related infections, particularly peri-implantitis, are inflammatory diseases caused by bacterial biofilms, leading to progressive destruction of surrounding tissues. Peri-implantitis not only may result in implant loss but also can trigger mo...

Unlocking Osseointegration—Surface Engineering Strategies for Enhanced Dental Implant Integration Academic Background Tooth loss is a prevalent issue faced by individuals of all ages worldwide. Dental implants, as a primary means of replacing missing teeth, depend largely on the speed and quality of osseointegration. Osseointegration refers to the ...

“PITX2 Expression and Neanderthal Introgression in HS3ST3A1 Contribute to Variation in Tooth Dimensions in Modern Humans” Source of the Research This paper was authored by Qing Li, Pierre Faux, Emma Wentworth Winchester, and others, and published on January 6, 2025, in the journal Current Biology. The authors come from various research institutions...