Multicentre Prospective Study on the Diagnostic and Prognostic Validity of Malnutrition Assessment Tools in Surgery

Medicine, Anesthesiology, Gastroenterology,
malnutrition   surgery   diagnostic tools   prognostic validity   multicentre study   nutritional assessment   postoperative complications  

Academic Background Malnutrition is a significant risk factor for postoperative complications, particularly in patients undergoing major abdominal surgery, where the incidence of malnutrition is high. However, there is currently no widely accepted tool for assessing malnutrition. Existing nutritional screening tools vary greatly in sensitivity and ...

ESICM Consensus-Based Recommendations for the Management of Very Old Patients in Intensive Care

Medicine, Emergency Medicine, Geriatrics, Anesthesiology,
critical care   delphi study   emergency medicine   geriatric medicine   very old patients  

ESICM Consensus: Management and Challenges of Very Old Patients in Critical Care Academic Background With the global aging population, the proportion of “very old patients” (aged 80 years and above) in intensive care units (ICUs) is rapidly increasing. This group is characterized by functional impairments and a high prevalence of complex multimorbi...

Evidence for Domain-General Arousal from Semantic and Neuroimaging Meta-Analyses Reconciles Opposing Views on Arousal

Medicine, Anesthesiology, Neurology, Life Sciences, Biophysics,
arousal   semantic analysis   neuroimaging   meta-analysis   natural language processing  

Neuroscientific Research Report on “Domain-General Arousal” Academic Background Arousal is a core concept in neuroscience, referring to fluctuations in brain and body states that underpin motivated behavior. Despite the widespread use of the term “arousal,” its definition has remained ambiguous, with differing interpretations in various textbooks. ...

Neurocritical Care Organization in Low-Income and Middle-Income Countries

Medicine, Emergency Medicine, Anesthesiology, Neurology,
neurocritical care   low-income countries   middle-income countries   critical care technologies   healthcare resource allocation  

Neurocritical Care Organization in Low- and Middle-Income Countries Academic Background and Problem Statement Neurocritical care (NCC) has rapidly evolved over the past few decades as a distinct subspecialty of critical care medicine. Evidence shows that patients with acute brain injuries have significantly improved outcomes when treated in dedicat...

Crystalloid Volume Versus Catecholamines for Management of Hemorrhagic Shock During Esophagectomy: Assessment of Microcirculatory Tissue Oxygenation of the Gastric Conduit in a Porcine Model Using Hyperspectral Imaging

Medicine, Anesthesiology, Gastroenterology, Oncology,
esophagectomy   hemorrhagic shock   hyperspectral imaging   porcine model   microcirculation   tissue oxygenation   crystalloid volume  

Study on Crystalloid Volume versus Catecholamine Strategies for Managing Hemorrhagic Shock during Esophagectomy Academic Background Esophageal cancer is a common malignant tumor worldwide, and surgical resection is one of the primary treatment methods. However, esophagectomy is a complex procedure involving two body cavities (thoracic and abdominal...

Reduced Oxycodone Brain Delivery in Rats due to Lipopolysaccharide-Induced Inflammation: Microdialysis Insights into Brain Disposition and Sex-Specific Pharmacokinetics

Medicine, Anesthesiology, Pharmacy,
blood-brain barrier   oxycodone   microdialysis   sex-specific   lipopolysaccharides   inflammation   pharmacokinetics  

The Impact of Inflammation on Brain Delivery of Oxycodone Academic Background Oxycodone is a widely used opioid analgesic with a unique property of being actively transported from the blood to the brain across the blood-brain barrier (BBB). This process is believed to be associated with the proton-coupled organic cation (H+/OC) antiporter system. H...