EDA2R Elevation in Liquid Biopsy Reflects Acute Brain Injury after Cranial Radiation Background Cranial radiation therapy is the standard treatment for advanced brain tumors and metastases, but it leads to devastating neurocognitive impairments, especially in childhood cancer survivors. As the number of childhood brain cancer survivors continues to...

Pediatric brainstem glioblastoma is the most common malignant brain tumor in children, and surgical resection is the primary treatment method. However, posterior fossa surgery may lead to a complication known as “Pediatric Cerebellar Mutism Syndrome (CMS).” CMS is primarily characterized by temporary mutism, motor disorders, and emotional abnormali...

This is a phase I clinical trial that explored the safety of preoperative single-fraction stereotactic radiosurgery (SRS) with dose escalation for patients with brain metastases. The background of this study is that for brain metastases larger than 2cm in diameter, surgery alone or single-fraction SRS alone is difficult to achieve ideal local contr...

This academic paper reports a study on exosomes in patients with glioblastoma. The study explored the potential application of exosomes as biomarkers in the diagnosis, prognosis, and treatment response monitoring of glioblastoma. Academic Background: Glioblastoma is an invasive brain tumor, and despite comprehensive treatments such as surgery, chem...

In this research paper from the journal Neuro-Oncology, the researchers investigated the relationship between the residual tumor cells at the resection margin after surgical removal and the progression-free survival (PFS) and overall survival (OS) in patients with wildtype isocitrate dehydrogenase (IDH wildtype) glioblastoma (GBM). The authors are ...