Oscillatory Contractile Forces Refine Endothelial Cell-Cell Interactions for Continuous Lumen Formation Governed by Heg1/CCM1

Academic Background The formation and maintenance of vascular networks are critical processes in embryonic development and tissue regeneration, involving the regulation of various biophysical forces. Endothelial cells (ECs) play a central role in angiogenesis and vasculogenesis, with the contractile forces of the cytoskeleton (actomyosin contractil...

Global Surveillance of Circulating MicroRNA for Diagnostic and Prognostic Assessment of Acute Myocardial Infarction Based on Plasma Small RNA Sequencing

Global Surveillance of Circulating MicroRNA for Diagnostic and Prognostic Assessment of Acute Myocardial Infarction Based on Plasma Small RNA Sequencing Academic Background Acute Myocardial Infarction (AMI) is one of the most severe cardiovascular diseases leading to human mortality and morbidity worldwide. The pathological mechanism of AMI primari...

Cardiac Dysfunction Among Breast Cancer Survivors: Role of Cardiotoxic Therapy and Cardiovascular Risk Factors

Report on the Study of Cardiac Dysfunction Among Breast Cancer Survivors Academic Background Breast cancer is the most common cancer diagnosed in women. Advances in early detection and novel therapeutics have yielded 5-year survival rates exceeding 90%. However, with over four million breast cancer survivors in the United States today, the quality ...

Effectiveness of a Cardiovascular Health Electronic Health Record Application for Cancer Survivors in Community Oncology Practice

Effectiveness of a Cardiovascular Health Electronic Health Record Application for Cancer Survivors in Community Oncology Practice Academic Background The cardiovascular health (CVH) of cancer survivors has become an increasingly important concern. Studies have shown that cancer survivors generally have poorer cardiovascular health, partly due to th...

Diagnostic Accuracy of Dynamic Stress Myocardial CT Perfusion in Patients with Stents: The ADVANTAGE 2 Study

Diagnostic Accuracy of Dynamic CT Perfusion in Patients with Coronary Stents Academic Background Coronary artery disease (CAD) is one of the leading causes of death worldwide. Percutaneous coronary intervention (PCI) is a common treatment for obstructive CAD. However, after stent implantation, patients may experience in-stent restenosis (ISR) or pr...

Prognostic Value of Coronary CT Angiography–Derived Quantitative Flow Ratio in Suspected Coronary Artery Disease

Prognostic Value of Coronary CT Angiography-Derived Quantitative Flow Ratio in Suspected Coronary Artery Disease Academic Background Coronary artery disease (CAD) is one of the leading causes of death and disability worldwide. Coronary CT angiography (CTA) is recommended as a first-line noninvasive test for patients with suspected or known CAD. CTA...