Photothermal MXene-Embedded Tannin–Eu3+ Particles as In Situ Bacterial Vaccines for Accelerating Healing of Wounds Infected by Seawater Immersion and Providing Persistent Anti-Infection Effects

Chemistry, Nanoscience, Materials Science, Medicine, Infectious Diseases, Life Sciences, Biochemistry, Bioengineering, Immunology,
MXene   Tannin   Wound Healing   Anti-infection   In Situ Vaccine  

Photothermal MXene-Embedded Tannin-Eu³⁺ Particles as In Situ Bacterial Vaccines for Seawater-Immersed Infected Wounds Academic Background Seawater-immersed wounds are prone to severe infections due to the low temperature, high salinity, and bacteria-rich environment, which hinder wound healing. Traditional antibacterial strategies often fail to pro...

Predicting Outcomes in Esophageal Squamous Cell Carcinoma Using scRNA-seq and Bulk RNA-seq: A Model Development and Validation Study

Medicine, Oncology, Life Sciences, Cell Biology, Immunology,
Esophageal squamous cell carcinoma   Glucose metabolism   Immune infiltration   Prognosis   Single-cell RNA sequencing   Bulk RNA sequencing   Bioinformatics  

Prognostic Prediction Model for Esophageal Squamous Cell Carcinoma Based on Single-Cell RNA Sequencing and Bulk RNA Sequencing Research Background Esophageal Squamous Cell Carcinoma (ESCC) is one of the most common malignant tumors globally, particularly prevalent in East Asia. Despite existing treatment methods such as surgery, endoscopic resectio...

Clinical Analysis of MOG Antibody-Associated Disease Overlapped with Anti-NMDA Receptor Encephalitis: A Long-Term Retrospective Study

Medicine, Neurology, Life Sciences, Immunology,
MOG antibody-associated disease   anti-NMDA receptor encephalitis   overlapping syndrome   clinical characteristics   radiological features   treatment   prognosis  

Clinical Analysis of MOG Antibody-Associated Disease Overlapping with Anti-NMDAR Encephalitis Background In recent years, with the in-depth study of autoimmune encephalitis (AE) and demyelinating diseases of the central nervous system (CNS), scientists have identified some rare cases of overlapping syndromes. Among them, the overlap between MOG Ant...

TDO2 Inhibition Counters Benzo[a]pyrene-Induced Immune Evasion and Suppresses Tumorigenesis in Lung Adenocarcinoma

Medicine, Oncology, Life Sciences, Biochemistry, Immunology,
Benzo[a]pyrene   TDO2   Immune evasion   Lung adenocarcinoma   Tryptophan metabolism   PD-L1   ICOSL  

The Role of TDO2 Inhibition in Lung Cancer Immune Evasion Background Introduction Lung cancer is one of the leading causes of cancer-related deaths worldwide, with smoking recognized as a primary cause of its occurrence. Cigarette smoke contains numerous carcinogens, among which benzo[a]pyrene (BAP), a polycyclic aromatic hydrocarbon, has been show...

Circulating Extracellular Vesicles as Promising Biomarkers for Precision Diagnostics: A Perspective on Lung Cancer

Medicine, Respiratory System, Oncology, Life Sciences, Biochemistry, Bioengineering, Immunology, Genetics, Biophysics,
extracellular vesicles   lung cancer   liquid biopsy   biosensors   early detection   precision medicine   nanotechnology  

Exosomes as Biomarkers for Precision Diagnosis of Lung Cancer Academic Background Lung cancer is one of the leading causes of cancer-related deaths worldwide, with early diagnosis and precision treatment of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) remaining significant challenges. Although traditional tissue biopsy is co...

Design of a Magnetic Nanoplatform Based on CD26 Targeting and HSP90 Inhibition for Apoptosis and Ferroptosis-Mediated Elimination of Senescent Cells

Design of a Magnetic Nanoplatform Based on CD26 Targeting and HSP90 Inhibition for Apoptosis and Ferroptosis-Mediated Elimination of Senescent Cells

Chemistry, Nanoscience, Medicinal Chemistry, Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Bioengineering, Immunology,
Iron oxide nanoparticles   CD26   HSP90 inhibitor   Drug-induced senescence   Skin cells   Senolysis  

Magnetic Nanoplatform Based on CD26 Targeting and HSP90 Inhibition for Apoptosis and Ferroptosis-Mediated Elimination of Senescent Cells Academic Background With the intensification of population aging, the accumulation of senescent cells is considered a significant hallmark of aging and age-related diseases. Senescent cells are not only associated...