Aβ-Aggregation-Generated Blue Autofluorescence Illuminates Senile Plaques as Well as Complex Blood and Vascular Pathologies in Alzheimer’s Disease

Blue Autofluorescence Generated by Aβ Aggregation Illuminates Senile Plaques and Complex Blood and Vascular Pathologies in Alzheimer’s Disease Research Background Alzheimer’s disease (AD) is a widespread neurodegenerative disorder globally, with senile plaques being the main pathological hallmark of AD, primarily composed of β-amyloid protein (Aβ)....

Smart (Splitting‑Merging Assisted Reliable) Independent Component Analysis for Extracting Accurate Brain Functional Networks

Smart Independent Component Analysis (SMART ICA): An Innovative Method for Extracting Accurate Brain Functional Networks Background Introduction In brain science research, Functional Networks (FNs) show great potential for understanding human brain function by exploring the integration and interaction relationships between different brain regions. ...

Compensation or Preservation? Different Roles of Functional Lateralization in Speech Perception of Older Non-Musicians and Musicians

The Impact of Music Training on Language Perception in Older Adults Under Global Aging Challenges Research Background As global population aging accelerates, the decline in language perception ability of older adults in noisy environments has become a notable issue. Older adults, even with normal hearing, often encounter the “cocktail party problem...

Sex-Dimorphic Kidney-Brain Connectivity Map of Mice

Sexual Dimorphism in the Mouse Kidney-Brain Connectome In recent years, an increasing number of studies have shown that kidney function is not only influenced by local self-regulation and hormonal systems but is also largely regulated by the nervous system. Although it is known that there are multi-synaptic anatomical connections between central au...

Neural Basis of Categorical Representations of Animal Body Silhouettes

Neural Mechanism | Neural Basis of Animal Body Silhouette Classification This article, written by Yue Pu and Shihui Han, published in “neurosci. bull.” in 2024, explores the neural processes of rapid classification and cognition of animal body silhouettes in humans. The study aims to reveal how humans identify and categorize individuals of differen...