Leptomeningeal Metastases in IDH-Wildtype Glioblastomas Revisited: Comprehensive Analysis of Incidence, Risk Factors, and Prognosis Based on Post-Contrast FLAIR

Comprehensive Analysis of Leptomeningeal Metastasis in IDH Wild-Type Glioblastoma In this article published in the journal “Neuro-Oncology,” the research team starting in 2024 delves into the incidence, risk factors, and prognosis of leptomeningeal metastases (LM) in patients with isocitrate dehydrogenase (IDH) wild-type glioblastoma. This study wa...

Raman-Based Machine Learning Platform Reveals Unique Metabolic Differences Between IDHmut and IDHwt Glioma

Study on Metabolic Differences between IDH Mutant and Wild-type Glioma Cells Using Raman Spectroscopy and Machine Learning Platform Background Introduction In the diagnosis and treatment of gliomas, formalin-fixed, paraffin-embedded (FFPE) tissue sections are commonly used. However, due to background noise interference from the embedding medium, th...

Diffusion-based Deep Learning Method for Augmenting Ultrastructural Imaging and Volume Electron Microscopy

Diffusion-based Deep Learning Method for Augmenting Ultrastructural Imaging and Volume Electron Microscopy

Enhancing Super-Resolution Imaging and Volume Electron Microscopy with Deep Learning Algorithms Based on Diffusion Models Background Introduction Electron Microscopy (EM) as a high-resolution imaging tool has made significant breakthroughs in cell biology. Traditional EM techniques are primarily used for two-dimensional imaging, and although they h...

Injectable Ultrasonic Sensor for Wireless Monitoring of Intracranial Signals

Injectable Ultrasonic Sensor for Wireless Monitoring of Intracranial Signals

Wireless Injectable Ultrasound Sensor for Intracranial Signal Monitoring Background Introduction Direct and accurate monitoring of intracranial physiological conditions is extremely important for injury classification, prognosis assessment, and disease prevention. However, traditional wired clinical devices, such as percutaneous leads, although per...

A Novel CNN-Based Image Segmentation Pipeline for Individualized Feline Spinal Cord Stimulation Modeling

Automated Spinal Cord Segmentation Pipeline Based on Convolutional Neural Network (CNN) for Individualized Cat Spinal Cord Stimulation Modeling Background and Research Motivation Spinal cord stimulation (SCS) is a widely used treatment method for chronic pain management. In recent years, it has also been used to modulate neural activity, aiming to ...