Report on Curcuma-Based Nutritional Supplements and the Risk of Age-Related Macular Degeneration Academic Background Age-related macular degeneration (AMD) is one of the leading causes of vision loss among elderly individuals, particularly in developed countries. There are two main types of AMD: non-exudative (dry) and exudative (wet). Dry AMD is c...

Report on the Economic Burden of Late-Stage Age-Related Macular Degeneration in Bulgaria, Germany, and the United States Academic Background Age-related macular degeneration (AMD) is a highly prevalent and debilitating retinal condition, affecting over 200 million people worldwide. Among them, late-stage AMD, which includes neovascular AMD (nAMD) a...

Racial Disparities in Genetic Detection Rates for Inherited Retinal Diseases Academic Background Inherited retinal diseases (IRDs) are a group of degenerative retinal disorders caused by genetic mutations, which can lead to vision loss or even blindness. With advances in gene discovery and next-generation DNA sequencing, an increasing number of pat...

Academic Background and Problem Statement Fibroblast growth factor receptor inhibitors (FGFRi) are a class of targeted drugs used to treat intrahepatic cholangiocarcinoma (iCCA). Although FGFRi has shown significant efficacy in treating iCCA, the potential complications associated with their long-term use have not been fully studied. In particular,...

Primary Open-Angle Glaucoma Polygenic Risk Score and Risk of Disease Onset: A Post Hoc Analysis Academic Background Primary open-angle glaucoma (POAG) is the most common form of glaucoma, often associated with elevated intraocular pressure (IOP). It is an irreversible optic neuropathy that, if untreated, can lead to vision loss. While IOP-lowering ...