REF-1 Overexpression in Neovascular Eye Diseases and Therapeutic Targeting with a Novel Inhibitor Academic Background Neovascular age-related macular degeneration (nAMD) is a common blinding eye disease predominantly affecting individuals aged 60 years and older. nAMD is characterized by the formation of subretinal neovascularization, leading to re...

Background With the widespread adoption of cataract surgery and lens replacement surgery, the optical performance of intraocular lenses (IOLs) has become increasingly critical in determining patients’ postoperative visual quality. Predicting clinical visual performance (such as visual acuity and defocus range) is an emerging area of interest in oph...

Research Advances on a Novel Compact Double-Pass Intraocular Scatter Measurement System Academic Background According to the World Health Organization (WHO), cataracts are the leading cause of blindness globally, accounting for approximately 50% of all blindness cases. More than 20 million people worldwide suffer from vision loss or severe impairme...

Demonstration of Femtosecond Laser Induced Refractive Index Change in Silk-Fibroin Hydrogels: A New Hope for Future Ophthalmic Biocompatible Implants In today’s era of advanced biotechnology and rapid developments in the biomedical field, refractive correction techniques have become a global research hotspot in ophthalmology. However, current corre...

Numerical Analysis Enhances Postoperative Visual Assessment and Optimization for Multifocal Intraocular Lenses (IOLs) Introduction and Research Background One of the main goals of cataract surgery is to achieve spectacle-free vision for patients. However, this goal is limited by two major challenges: loss of accommodative function and postoperative...