Stochastically Structured Illumination Microscopy: Scan-less Super Resolution Imaging

Report on Stochastic Structured Illumination Microscopy (S2IM): Scan-less Super-Resolution Imaging Academic Background In the field of super-resolution microscopy, traditional Structured Illumination Microscopy (SIM) techniques rely on precise mechanical control and micron-scale optical alignment to achieve high-resolution imaging. However, these t...

Gut Microbiota-Derived Indole-3-Acetic Acid Suppresses High Myopia Progression by Promoting Type I Collagen Synthesis

Gut Microbiota-Derived Indole-3-Acetic Acid (3-IAA) Suppresses High Myopia Progression by Promoting Type I Collagen Synthesis Background High myopia (HM) is a serious vision-threatening ocular condition associated with complications such as glaucoma, cataracts, and macular degeneration. Currently, effective interventions for high myopia are lacking...

Serine and Glycine Physiology Reversibly Modulate Retinal and Peripheral Nerve Function

Reversible Regulation of Retinal and Peripheral Nerve Function: Physiological Study of Serine and Glycine Background and Research Motivation Macular Telangiectasia Type 2 (Mactel) is an age-related retinal disease characterized by central vision loss. The molecular etiology of this disease is complex and is primarily associated with the metabolism ...

Natural Killer Cells Promote Neutrophil Extracellular Traps and Restrain Macular Degeneration in Mice

Study on Macular Degeneration Reveals Inhibitory Effect of Natural Killer Cells on Disease Progression Background Age-related Macular Degeneration (AMD) is the leading cause of irreversible blindness among the elderly globally. With an aging population, the incidence of AMD is significantly increasing. Early features of AMD include the accumulation...

Diabetic Retinopathy is a Ceramidopathy Reversible by Anti-Ceramide Immunotherapy

Diabetic Retinopathy as a Ceramide Disease Reversible by Anti-Ceramide Immunotherapy Background Diabetic Retinopathy (DR) is one of the most common metabolic disorders worldwide. Diabetes not only leads to chronic complications in macrovascular and microvascular systems but also imposes significant socio-economic burdens. As a microvascular complic...