Multimodal Imaging Study of the Tumor Microenvironment in Colorectal Cancer: Revealing Spatial Heterogeneity Academic Background Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, with its complexity and heterogeneity posing significant challenges for treatment and prognosis prediction. The tumor microe...

Rapid 3D Imaging at Cellular Resolution for Digital Cytopathology with a Multi-Camera Array Scanner (MCAS) Academic Background Optical microscopy has long been the standard method for diagnosis in cytopathology. However, traditional whole-slide scanners, while capable of automatically imaging and digitizing large sample areas, are slow and expensiv...

Academic Background Three-dimensional (3D) high-resolution large-volume imaging has remained a significant challenge in the field of biomedical research. Traditional two-dimensional (2D) slice imaging, while capable of providing planar morphological information of tissues and cells, fails to comprehensively display internal 3D structural informatio...

Impact of Dietary Zinc on Stimulated Zinc Secretion MRI in the Healthy and Malignant Mouse Prostate Academic Background Zinc (Zn²⁺) is an essential trace element in biological systems, participating in various physiological processes, including enzyme catalysis, structural regulation of transcription factors, immune system modulation, and cell prol...

Uranium-Free KMnO₄/Pb Staining Enables Imaging of Tissue Architectures in Low Vacuum Scanning Electron Microscopy Academic Background Electron Microscopy (EM) is one of the most powerful tools for studying the ultrastructure of cells and tissues. However, traditional metal staining methods for biological samples often require the use of harmful ura...