A Time-Scheduled Oxygen Modulation System Facilitates Bone Regeneration by Powering Periosteal Stem Cells

Medicine, Orthopedics, Basic Medical Sciences, Life Sciences, Cell Biology, Biochemistry, Bioengineering,
bone regeneration   periosteal stem cells   remote control   oxygen delivery   rapid neovascularization  

Academic Background During tissue repair, chronic hypoxia negatively impacts the functionality of stem cells. Periosteal Stem Cells (PSCs), as the primary contributors to bone repair, exhibit unclear behavior under hypoxic conditions. While hypoxia may be beneficial for certain stem cells in the early stages of tissue repair, prolonged hypoxia can ...

A Polyphenol–Metal Network of Propyl Gallate Gallium/Hafnium Oxide on Polyimide Fibers for Facilitating Ligament–Bone Healing

Chemistry, Polymer Chemistry, Materials Science, Organic Polymeric Materials, Medicine, Orthopedics, Sports Medicine, Life Sciences, Bioengineering,
polyimide fiber   artificial ligament   osteogenesis   anti-bacteria   anti-inflammation   ligament–bone healing  

Study on Surface Modification of Polyimide Fibers to Promote Ligament-Bone Healing Academic Background Anterior Cruciate Ligament (ACL) injury is one of the most common sports injuries worldwide, with approximately 1 in 1,250 people requiring ACL reconstruction surgery each year. Currently, the main methods for ACL reconstruction include autografts...

Quantitative Ultrasonic Backscatter Evaluation of Elastic and Mechanical Properties in a Rabbit Tendinopathy Healing Model

Medicine, Orthopedics, Medical Imaging, Life Sciences, Bioengineering,
ultrasound backscatter   tendinopathy   elastic properties   mechanical properties   quantitative evaluation  

Application of Ultrasound Backscatter Technique in Quantitative Tendon Characterization Academic Background Tendinopathy is a common musculoskeletal disease characterized by alterations in the microstructure, composition, and cellular organization of tendons, leading to pain and decreased function. Tendinopathy is typically initiated by overuse and...

Estrogen Deficiency Alters Vascularization and Mineralization Dynamics: Insight from a Novel 3-D Humanized and Vascularized Bone Organoid Model

Medicine, Orthopedics, Endocrinology, Life Sciences, Bioengineering,
osteoporosis   vascularization   mineralization   3D model   estrogen deficiency  

The Impact of Estrogen Deficiency on Vascularization and Mineralization Dynamics—Insights from a Novel 3D Humanized and Vascularized Bone Organoid Model Academic Background Osteoporosis is a common bone disease, particularly prevalent among postmenopausal women. Osteoporosis not only manifests as a reduction in bone mass but also involves changes i...

Exoskeleton-Assisted Stance and Kneeling Balance and Work Task Evaluation in Construction

Engineering, Mechanical Engineering, Architecture and Civil Engineering, Information Science, Automation, Artificial Intelligence, Medicine, Orthopedics,
exoskeleton   construction workers   balance control   virtual reality   welding tasks   knee joint   fall risk reduction  

Balance and Task Evaluation of Construction Workers Assisted by Knee Exoskeletons Background Introduction Construction workers face serious safety and health risks in hazardous working environments, especially when working at heights. Prolonged standing and kneeling postures can lead to knee injuries, musculoskeletal disorders, and visual disturban...