Exposure to School Racial Segregation and Late-Life Cognitive Outcomes

Academic Report on the Study “Exposure to School Racial Segregation and Late-Life Cognitive Outcomes” In recent years, the prevalence of Cognitive Impairment and Dementia among the elderly has been on the rise. In the U.S., significant disparities in cognitive health exist between non-Hispanic Black individuals and non-Hispanic White individuals. R...

A Couple-Based Intervention for Chinese Older Adults with Type 2 Diabetes: A Randomized Clinical Trial

Report on the Management of Chinese Older Adults with Type 2 Diabetes through Couple-Based Interventions: A Randomized Clinical Trial Academic Background Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases globally, particularly common among older adults. China has the largest number of diabetes patients worldwide, reachin...

Recombinant vs Egg-Based Quadrivalent Influenza Vaccination for Nursing Home Residents: A Cluster Randomized Trial

Comparative Analysis of Recombinant Quadrivalent Influenza Vaccine and Standard Egg-Based Quadrivalent Influenza Vaccine in Nursing Home Residents: A Cluster Randomized Trial Academic Background Influenza is among the primary respiratory pathogens causing morbidity and mortality among the elderly worldwide, particularly in nursing home residents wh...

The Influences of APOE Isoforms on Endothelial Adherens Junctions and Actin Cytoskeleton Responding to MCRP

Research Background Alzheimer’s Disease (AD) is a common neurodegenerative disorder characterized by the deposition of amyloid-beta (Aβ) plaques and abnormal phosphorylation of tau protein. Recent studies have increasingly highlighted the role of cerebrovascular alterations in the pathogenesis of AD. Specifically, endothelial cell damage and inflam...

Lithocholic Acid Phenocopies Anti-Ageing Effects of Calorie Restriction

Lithocholic Acid Phenocopies Anti-Ageing Effects of Caloric Restriction Academic Background Caloric restriction (CR) is a dietary intervention used to promote health and longevity by reducing food intake. Although CR has been shown to extend the lifespan of various organisms, the specific metabolic mechanisms behind its effects remain unclear. In p...