Background Introduction Spinal Cord Injury (SCI) is a significant challenge in the medical field, particularly in terms of neural function recovery. Research indicates that neurons play a crucial role in spinal cord regeneration, but in complex pathological environments, neurons are influenced by various factors, leading to rapid senescence. Senesc...

Academic Background The regenerative capacity of the nervous system varies significantly between different regions. Axons in the peripheral nervous system (PNS) can regenerate spontaneously after injury, whereas axons in the central nervous system (CNS) lack this ability. This difference makes recovery after CNS injury extremely challenging, especi...

Radiation-Induced Cellular Plasticity Primes Glioblastoma for Forskolin-Mediated Differentiation Academic Background Glioblastoma (GBM) is one of the deadliest brain cancers in adults, with a median survival period of only 15 to 18 months for patients. Although surgery combined with chemoradiotherapy can delay disease progression, these treatments ...

The Role of Notch, ERK, and SHH Signaling Pathways in the Fate Determination of Cortical Glial Cells and Olfactory Bulb Interneurons Academic Background During cortical development, neurogenesis and gliogenesis are two closely connected stages. Neurogenesis primarily generates neurons, while gliogenesis produces glial cells, including astrocytes an...

Research on Real-Time 3D Reconstruction and Navigation in Neuroendoscopy Based on Self-Supervised Learning Academic Background Neuroendoscopic surgery, as a minimally invasive surgical technique, is widely used in the treatment of deep brain lesions, such as endoscopic third ventriculostomy (ETV), choroid plexus cauterization, and cyst fenestration...