From Bedside to Bench: New Insights in Epilepsy-Associated Tumors Based on Recent Classification Updates and Animal Models on Brain Tumor Networks

Latest Research on Epilepsy-Associated Tumors: Classification and Animal Models Background Epilepsy is a common neurological disorder, and some patients are accompanied by brain tumors, particularly low-grade neuroepithelial tumors (LGNTs). These tumors typically grow slowly but are highly associated with drug-resistant epilepsy. Although research ...

The Multifaceted Therapeutical Role of Low-Density Lipoprotein Receptor Family in High-Grade Glioma

The Multifaceted Therapeutic Role of the Low-Density Lipoprotein Receptor Family in High-Grade Glioma Academic Background High-grade gliomas (HGG) are the most aggressive and prevalent primary brain tumors in the central nervous system (CNS), accounting for approximately 80% of all malignant brain tumors. Among them, glioblastoma (GBM) is the most ...

Relaxin-2 Attenuates Oxidative Stress and Neuronal Apoptosis via the ERK-nNOS-NO Pathway After Germinal Matrix Hemorrhage in Rats

rh-relaxin-2 Attenuates Oxidative Stress and Neuronal Apoptosis via the ERK-nNOS-NO Pathway After Germinal Matrix Hemorrhage in Rats Academic Background Germinal Matrix Hemorrhage (GMH) is one of the most common neurological disorders in newborns, particularly in preterm infants, and is a major cause of brain injury. GMH not only triggers acute inf...

Research Priorities for Improving Cognitive and Neuropsychological Outcomes in Hydrocephalus

Research Priorities for Improving Cognitive and Neuropsychological Outcomes in Hydrocephalus Academic Background Hydrocephalus is a neurological disorder affecting approximately 85 per 100,000 individuals worldwide. It is closely associated with motor and cognitive impairments. Although advancements in surgical interventions have significantly impr...

Phase-Contrast MRI Analysis of Cerebral Blood and CSF Flow Dynamic Interactions

Study on the Interaction Between Cerebral Blood Flow and Cerebrospinal Fluid Dynamics Measured at Intracranial and Extracranial Planes Background The interaction between cerebral blood flow (CBF) and cerebrospinal fluid (CSF) is a critical factor in maintaining intracranial pressure (ICP) stability. According to the Monro-Kellie doctrine, the intra...