Scientific Research Report Background Introduction Breast cancer is the most commonly diagnosed cancer worldwide among both men and women, and it is the leading cause of cancer-related deaths in women. The standard treatment for early-stage breast cancer usually involves surgery and (neo)adjuvant chemotherapy and/or endocrine therapy, aiming to eli...

Clinical Validation of AI-based Interpretation of PD-L1 Tumor Proportion Score in Predicting Response to Immune Checkpoint Inhibitors in Non-small Cell Lung Cancer In the field of tumor treatment and diagnosis, the assessment of PD-L1 (Programmed Death-Ligand 1) Tumor Proportion Score (TPS) is a critical task, especially in predicting the response ...

Background of Urgent Problem Prostate cancer is one of the most common cancers among men. Metastatic castration-resistant prostate cancer (mCRPC) is an advanced form of prostate cancer characterized by resistance to castration therapy. Radium-223 is an α-emitting radiopharmaceutical that has been shown to improve overall survival (OS) and reduce sk...

Latest Research in Lung Cancer Genomics: Analysis of Circulating Tumor DNA Detection in Non-Small Cell Lung Cancer Background and Motivation In recent years, the treatment of non-small cell lung cancer (NSCLC) has seen significant changes due to the success of targeted therapies. The National Comprehensive Cancer Network guidelines recommend extens...

Screening and Outcomes of Hereditary Cancer Syndromes: A Study at an Urban Safety Net Hospital Study Background Patients with Hereditary Cancer Syndromes (HCS) have a higher lifetime risk of developing cancer. Historically, underserved populations have lower rates of genetic evaluation. Hence, researchers aim to understand the demographic factors i...