Genomic Profiling of Rare Undifferentiated Sarcomatoid Subtypes of Pancreatic Carcinomas: In Search of Therapeutic Targets

Genomic Characteristics of a Rare Pancreatic Cancer Undifferentiated Sarcomatoid Carcinoma Subtype Academic Background Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest cancers, characterized by early invasion and metastasis. Undifferentiated Sarcomatoid Carcinoma (USC) is a particularly aggressive but rare subtype of PDAC, accounting...

Towards Machine Learning-Based Quantitative Hyperspectral Image Guidance for Brain Tumor Resection

Towards Machine Learning-Based Quantitative Hyperspectral Image Guidance for Brain Tumor Resection

Study on the Role of Machine Learning-Assisted Quantitative Hyperspectral Imaging in Brain Tumor Resection Background Introduction Complete resection of malignant gliomas has always been challenged by the difficulty of distinguishing tumor cells in invasive regions. The background of this study is: In neurosurgery, the application of 5-aminolevulin...

Unified Metagenomic Method for Rapid Detection of Microorganisms in Clinical Samples

Unified Metagenomic Method for Rapid Detection of Microorganisms in Clinical Samples

Research on a Unified Metagenomic Method for Rapid Detection of Microorganisms in Clinical Samples Background Introduction The background of this research is based on the current limitations of clinical metagenomics. Clinical metagenomics involves genome sequencing of all microorganisms in clinical samples, ideally performed after depleting human D...

Mapping Multimorbidity Progression

Mapping Multimorbidity Progression Among 190 Diseases Background Globally, with the aging population and the significant increase in the negative impacts of chronic diseases, multimorbidity, the coexistence of multiple long-term conditions, has become an increasingly severe health challenge. Understanding the accumulation process of multimorbidity ...

The Mediating Role of Systemic Inflammation and Moderating Role of Racialization in Disparities in Incident Dementia

The Mediating Role of Systemic Inflammation in the Differences in Cognitive Disease Incidence and the Moderating Role of Racialization This study examines the link between systemic racism and the increased burden of cognitive disease. Researchers investigated the mediating role of C-reactive protein (CRP) as a marker of systemic inflammation in the...