Detection of Odorants in Odour Mixtures Among Healthy People and Patients with Olfactory Dysfunction

Detection of Target Odorants in Odor Mixtures Among Healthy Individuals and Patients with Olfactory Dysfunction Academic Background In daily life, most of the odors we encounter are mixtures rather than single odorants. However, the mechanisms underlying human perception of odor mixtures are far less understood than those of single odorants. The pe...

Transcranial Magnetic Stimulation Inter-Pulse Interval Does Not Influence Corticospinal Excitability to the Biceps Brachii During Submaximal Isometric Elbow Flexion

The Effect of Transcranial Magnetic Stimulation Inter-Pulse Interval on Corticospinal Excitability of the Biceps Brachii Research Background Transcranial Magnetic Stimulation (TMS) is a non-invasive neurophysiological research technique widely used to assess corticospinal excitability in both healthy individuals and clinical patients. By applying e...

Topological Features of Brain Functional Networks Are Reorganized During Chronic Tinnitus: A Graph-Theoretical Study

Reorganization of Topological Features in Brain Functional Networks in Patients with Chronic Tinnitus Academic Background Tinnitus is the perception of sound in the absence of any external acoustic stimuli or internal sources of auditory perception, with a global prevalence ranging from 11.9% to 30.3%. Patients with tinnitus experience not only aud...

Laser-Induced Olfactory Bulbectomy in Adult Zebrafish as a Novel Putative Model for Affective Syndrome: A Research Tribute to Brian Leonard

Study on Laser-Induced Olfactory Bulbectomy in Zebrafish as a Novel Model for Affective Syndrome Background Affective disorders, such as depression, are common mental health issues worldwide. Although rodent models have played a significant role in depression research, their cross-species applicability has limitations. Zebrafish (Danio rerio), as a...

Basal Ganglia and Related Disorders: From Cellular and Circuit Dysfunctions to Therapy

The Interaction Between A2A Receptor and CB1 Receptor in GABA and Glutamate Release in the Basal Ganglia Background The basal ganglia are key structures in the brain responsible for motor control and reward-based behaviors. They receive excitatory inputs from the cortex and thalamus, with 80% of the synapses being glutamatergic, while the second mo...

Clinical Analysis of MOG Antibody-Associated Disease Overlapped with Anti-NMDA Receptor Encephalitis: A Long-Term Retrospective Study

Clinical Analysis of MOG Antibody-Associated Disease Overlapping with Anti-NMDAR Encephalitis Background In recent years, with the in-depth study of autoimmune encephalitis (AE) and demyelinating diseases of the central nervous system (CNS), scientists have identified some rare cases of overlapping syndromes. Among them, the overlap between MOG Ant...