Cyanobacteria–Probiotics Symbionts for Modulation of Intestinal Inflammation and Microbiome Dysregulation in Colitis Academic Background Inflammatory Bowel Disease (IBD) is a group of chronic inflammatory conditions of the gut, primarily including Crohn’s Disease (CD) and Ulcerative Colitis (UC). The pathogenesis of IBD is complex, involving dysfun...

Optimized Nutritional Interventions Improve Muscle Fatigue, Strength, and Quality of Life in Patients with Primary Mitochondrial Disease Background Introduction Primary mitochondrial disease (PMD) encompasses a group of disorders caused by mutations in mitochondrial DNA or nuclear DNA, affecting systemic energy metabolism. The prevalence is approxi...

Gut Microbiota-Derived Indole-3-Acetic Acid (3-IAA) Suppresses High Myopia Progression by Promoting Type I Collagen Synthesis Background High myopia (HM) is a serious vision-threatening ocular condition associated with complications such as glaucoma, cataracts, and macular degeneration. Currently, effective interventions for high myopia are lacking...

Inflammation-Induced Epigenetic Imprinting and Intestinal Stem Cell Regulation In recent years, the scientific community has shown immense interest in the “memory” capabilities of non-immune cells, particularly the phenomenon where specific stem cells in adult tissues develop memory after undergoing inflammation, influencing their functionality. Ho...

Multilayered Tissue Construction of a Micro-intestinal System Reproduces Mesenchymal Flow Research Background In recent years, constructing in vitro models of the human small intestine has made significant progress; however, fully replicating its complex structural and functional characteristics remains challenging. The goal of micro-intestinal tis...