PSMA PET/CT-based Multimodal Deep Learning Model for Accurate Prediction of Pelvic Lymph-Node Metastases in Prostate Cancer

Information Science, Artificial Intelligence, Medicine, Urology, Medical Imaging, Oncology,
prostate cancer   lymph node metastases   prostate-specific membrane antigen   PET/CT   deep learning  

In-depth Analysis of PSMA PET/CT-based Multimodal Deep Learning Model for Predicting Lymph Node Metastases in Prostate Cancer Patients Background Prostate cancer (PCA) is one of the most common malignant tumors in men and a leading cause of cancer-related deaths. In clinically localized prostate cancer patients, extended pelvic lymph node dissectio...

Imaging Biomarkers of Cognitive Impairment in Parkinson’s Disease

Medicine, Neurology, Medical Imaging,
Parkinson's disease   Cognitive decline   Imaging biomarkers   [18F]FDG PET   MRI   Neurodegeneration   Diffusion-weighted imaging  

Multimodal Neuroimaging Study on Cognitive Impairment in Parkinson’s Disease Parkinson’s Disease (PD) is a common neurodegenerative disorder mainly characterized by motor impairments. However, cognitive impairment (CI), one of the non-motor symptoms, significantly affects patients’ quality of life. According to extensive epidemiological studies, ap...

The Practical Advantage of One-Day Dual-Tracer Examination in Neuroendocrine Neoplasms Using Low-Activity LAFOV PET Imaging

Medicine, Medical Imaging, Oncology,
neuroendocrine neoplasms   dual-tracer PET   LAFOV PET/CT   low activity [18F]FDG PET   [18F]sifalin-tate   imaging diagnostics   therapeutic strategies  

Breakthrough in Nuclear Medicine and Molecular Imaging: European Study Reveals Application of One-Day Dual-Tracer PET/CT Imaging in Neuroendocrine Tumors In the field of nuclear medicine, neuroendocrine neoplasms (NENs), known for their heterogeneity and complexity, have consistently been a focal point of research. A team from Tübingen, Germany, ha...

An Explainable Transformer Model Integrating PET and Tabular Data for Histologic Grading and Prognosis of Follicular Lymphoma: A Multi-Institutional Digital Biopsy Study

Information Science, Artificial Intelligence, Medicine, Medical Imaging, Oncology,
follicular lymphoma   PET/CT   histologic grade   prognosis   transformer model   digital biopsy   multimodal  

A Transformer Model Integrating PET Imaging and Clinical Data: A Multicenter Digital Biopsy Study for Predicting Pathological Grading and Prognosis of Follicular Lymphoma Academic Background Follicular Lymphoma (FL) is the most common indolent Non-Hodgkin Lymphoma in Western countries, accounting for approximately 30% of newly diagnosed cases. Acco...

Transcriptionally Downregulated GABAergic Genes Associated with Synaptic Density Network Dysfunction in Temporal Lobe Epilepsy

Medicine, Neurology, Medical Imaging, Life Sciences, Biochemistry, Genetics,
Temporal Lobe Epilepsy   Synaptic Density Network   SV2A PET   Gene Expression   GABAergic Inhibition  

Revealing Gene Expression Patterns Associated with Synaptic Density Network Dysfunction in Temporal Lobe Epilepsy Background Temporal Lobe Epilepsy (TLE) is the most common form of focal epilepsy, and its pathological features and mechanisms have long drawn extensive attention in the field of neuroscience. This disorder involves not only a single b...

Impact of FAPI Molar Dose on Targeted PET Imaging and Therapy in Mouse Syngeneic Tumor Models

Medicine, Medical Imaging, Oncology,
Molar dose   Targeted imaging   Mouse models   Radiotherapy   FAPI   Cancer-associated fibroblasts   Preclinical research  

Background In recent years, significant progress has been made in the field of cancer diagnosis and treatment, particularly in technologies based on molecular imaging and targeted radiotherapy. Among these, Fibroblast Activation Protein (FAP), a biomarker highly expressed in the tumor microenvironment, has garnered widespread attention. FAP is prim...