Optical Coherence Tomography Guided Automatic Robotic Craniotomy Surgery Platform

Optical Coherence Tomography Guided Automatic Robotic Craniotomy Surgery Platform

Information Science, Automation, Medicine, Neurology, Neurosurgery, Medical Imaging, Life Sciences, Bioengineering,
optical coherence tomography   automated craniotomy   robotic surgery   cranial window   brain research   high-resolution imaging  

Research Report on Automated Robotic Craniotomy Surgery System Background As the central organ of complex life activities, the brain governs all psychological and conscious processes, playing a crucial role in every aspect of life. Entering the 21st century, neuroscience has become one of the fastest-growing and most prominent fields, with animal m...

Development of Next Generation Low-Cost OCT Towards Improved Point-of-Care Retinal Imaging

Medicine, Ophthalmology, Medical Imaging, Life Sciences, Bioengineering, Biophysics,
Optical Coherence Tomography   Low-Cost   Retinal Imaging   Point-of-Care   Image Quality   Clinical Research   Balanced Detection  

Development of Next-Generation Low-Cost Optical Coherence Tomography (OCT) Systems: Advancing Retinal Imaging for Clinical Applications Academic Background Optical Coherence Tomography (OCT) is a non-invasive, high-resolution imaging technology widely used in ophthalmology, particularly for diagnosing retinal diseases. However, existing commercial ...

Spatial Multiomic Landscape of the Human Placenta at Molecular Resolution

Medicine, Obstetrics and Gynecology, Life Sciences, Cell Biology, Biochemistry, Immunology,
placenta   multiomics   molecular resolution   gene regulation   pregnancy complications  

A New Chapter in the Molecular Understanding of the Human Placenta: Breakthroughs in Spatial Multiomics Background and Research Questions The placenta is the first fetal organ to develop during human pregnancy and plays a critical role in ensuring successful gestation and healthy fetal development. Despite its importance, our understanding of the m...

Gene-Level Alignment of Single-Cell Trajectories

Medicine, Life Sciences, Cell Biology, Immunology, Genetics,
single-cell RNA sequencing   pseudotime trajectory inference   dynamic time warping   gene expression   cell state  

Gene-level Single-cell Trajectory Alignment: A New Method Based on Dynamic Programming The advent of single-cell RNA sequencing (scRNA-seq) technology has dramatically advanced biological research, enabling scientists to observe dynamic changes at the single-cell level over time and space. However, comparing such dynamics across samples or conditio...

Single-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis

Medicine, Oral Sciences, Life Sciences, Immunology,
periodontitis   single-cell RNA sequencing   keratinocytes   immune interactions   bacterial infection   spatial phenotyping   chronic inflammation  

Single-Cell and Spatially Resolved Interactomics of Tooth-Associated Keratinocytes: Exploring the Role of Structural Immunity in Periodontitis Background Periodontitis is a chronic inflammatory disease that affects the periodontal tissues and impacts billions of people globally, potentially resulting in tooth loss. It is primarily caused by polybac...

Super-Resolution Imaging of Fast Morphological Dynamics of Neurons in Behaving Animals

Medicine, Neurology, Medical Imaging, Life Sciences, Biophysics,
super-resolution imaging   neuronal morphological dynamics   behaving animals   structured illumination microscopy   neural plasticity  

Super-Resolution Imaging Reveals New Advances in Neural Morphodynamics in Mouse Brains: Dynamic Observations in Head-Fixed Awake Animals Background In the field of neuroscience, understanding the morphological changes and functional dynamics of neurons is key to deciphering how the brain processes information and sustains network plasticity. Despit...