Diagnostic Accuracy and Value of CXCR4-Targeted PET/MRI Using 68Ga-Pentixafor for Tumor Localization in Cushing Disease

Medicine, Endocrinology, Neurosurgery, Medical Imaging,
Cushing Disease   68Ga-Pentixafor   PET/MRI   CXCR4   Tumor Localization   Diagnostic Accuracy   Pituitary Tumors  

Diagnostic Accuracy and Value of 68Ga-Pentixafor PET/MRI in Tumor Localization for Cushing’s Disease Academic Background Cushing’s disease is the primary cause of Cushing’s syndrome, characterized by excessive secretion of adrenocorticotropic hormone (ACTH) from the pituitary gland, often due to pituitary adenomas. Patients with chronic hypercortis...

Alterations in Volume and Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder

Medicine, Psychiatry, Neurology, Medical Imaging,
Opioid Use Disorder   Brain MRI   Resting-State Functional Connectivity   Neuroimaging   Structural Alterations   Functional Alterations   Brain Volume  

Multimodal Neuroimaging Study of Structural and Functional Brain Alterations in Individuals with Opioid Use Disorder Academic Background Opioid Use Disorder (OUD) is a complex chronic condition that has multifaceted negative impacts on an individual’s life and is closely associated with an increased risk of mortality. In 2021, over 80,000 deaths in...

MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID

Medicine, Neurology, Medical Imaging,
Long COVID   Mitochondrial Dysfunction   MR Spectroscopy   Fatigue   Muscle Metabolism  

Report on the Use of MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID Academic Background The COVID-19 pandemic has had a profound impact on global health, with many patients experiencing prolonged symptoms even after recovery, commonly referred to as “Long COVID” or “Post–COVID-19 Condition” (PCC). These symptoms include fa...

NACVI-RADS Scores for Assessing Muscle-Invasive Bladder Cancer Response to Neoadjuvant Immunotherapy with Multiparametric MRI

Medicine, Urology, Medical Imaging, Oncology,
Muscle-Invasive Bladder Cancer   Neoadjuvant Immunotherapy   Multiparametric MRI   NACVI-RADS Scores   Pathologic Complete Response  

Academic Background Muscle-invasive bladder cancer (MIBC) is a highly aggressive malignancy. The standard treatment typically involves cisplatin-based neoadjuvant chemotherapy (NAC) or immunotherapy, followed by radical cystectomy (RC) and bilateral pelvic lymph node dissection. However, radical cystectomy significantly impacts patients’ quality of...

Osteochondral Abnormalities on Three-Dimensional Ultrashort Echo Time MRI Scans Are Associated with Knee Cartilage Degradation

Medicine, Rheumatology and Immunology, Orthopedics, Medical Imaging,
osteochondral abnormalities   knee cartilage degradation   three-dimensional ultrashort echo time MRI   osteochondral junction abnormalities   cartilage degradation grade  

Osteochondral Abnormalities on Three-Dimensional Ultrashort Echo Time MRI Scans Are Associated with Knee Cartilage Degradation Academic Background Osteoarthritis (OA) is the most prevalent musculoskeletal disease, characterized by pain and disability. A hallmark of OA is the progressive loss of articular hyaline cartilage, which connects to the sub...

CT- and MRI-Based Factors Associated with Rapid Growth in Early-Stage Hepatocellular Carcinoma

Medicine, Hepatobiliary System, Medical Imaging, Oncology,
Hepatocellular Carcinoma   Tumor Growth Rate   LI-RADS Categories   CT   MRI  

Imaging-Based Factors Associated with Rapid Growth in Early-Stage Hepatocellular Carcinoma Academic Background Hepatocellular carcinoma (HCC) is the most common primary liver cancer globally and the third leading cause of cancer-related mortality, with increasing incidence and mortality rates reported in North America, South America, and Europe. Al...