Regulatory T Cells-Related Gene in Primary Sclerosing Cholangitis: Evidence from Mendelian Randomization and Transcriptome Data

Medicine, Hepatobiliary System, Medical Laboratory Science, Gastroenterology, Life Sciences, Immunology, Genetics,
Primary Sclerosing Cholangitis   Regulatory T Cells   Mendelian Randomization   Transcriptome Data   Machine Learning   Immune Cell Infiltration   Molecular Pathways  

Regulatory T Cells-Related Gene in Primary Sclerosing Cholangitis: Evidence from Mendelian Randomization and Transcriptome Data Authors: Jianlan Hu1, Youxing Wu1, Danxia Zhang1, Xiaoyang Wang1, Yaohui Sheng1, Hui Liao1, Yangpeng Ou2✉, Zhen Chen3, Baolian Shu1✉, and Ruohu Gui1✉ Journal: Genes & Immunity (2024) 25:492–513 DOI: https://doi.org/10.1038...

Neoantigen-Specific mRNA/DC Vaccines for Effective Anticancer Immunotherapy

Medicine, Oncology, Life Sciences, Immunology,
neoantigen   mRNA vaccine   dendritic cells   anticancer immunotherapy   personalized treatment  

Effectiveness of Neoantigen-Specific mRNA/DC Vaccines in Anticancer Immunotherapy Academic Background Cancer immunotherapy has emerged as a significant breakthrough in cancer treatment in recent years. Among the various approaches, dendritic cell (DC) vaccines have shown potential in extending the survival of some advanced cancer patients. However,...

Revolutionary Self-Powered Transducing Mechanism for Long-Lasting and Stable Glucose Monitoring: Achieving Selective and Sensitive Bacterial Endospore Germination in Microengineered Paper-Based Platforms

Engineering, Electrical Engineering, Medicine, Endocrinology, Life Sciences, Bioengineering, Microbiology,
glucose monitoring   self-powered transduction   bacterial spore germination   microengineered platforms   diabetes management  

Revolutionary Self-Powered Glucose Monitoring Mechanism: Microengineered Paper-Based Platform with Microbial Spores Academic Background Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels, which can lead to severe complications such as cardiovascular diseases, retinopathy, kidney failure, and neuropathy. The glob...

Automated Analysis of Ultrastructure through Large-Scale Hyperspectral Electron Microscopy

Automated Analysis of Ultrastructure through Large-Scale Hyperspectral Electron Microscopy

Medicine, Medical Laboratory Science, Medical Imaging, Life Sciences, Cell Biology, Bioengineering, Biophysics,
electron microscopy   hyperspectral imaging   biological ultrastructure   automated analysis   elemental mapping  

Automated Analysis of Ultrastructure: A Study Based on Large-Scale Hyperspectral Electron Microscopy Academic Background Electron Microscopy (EM) is a key technique for studying biological ultrastructure, revealing the fine details of cells at biomolecular resolution. In recent years, advancements in automation and digitization have enabled EM to c...

Fiber Optics-Based Surface Enhanced Raman Spectroscopy Sensors for Rapid Multiplex Detection of Foodborne Pathogens in Raw Poultry

Chemistry, Analytical Chemistry, Engineering, Electrical Engineering, Medicine, Infectious Diseases, Life Sciences, Bioengineering, Microbiology,
Surface Enhanced Raman Spectroscopy   Foodborne Pathogens   Raw Poultry   Multiplex Detection   Fiber Optics Sensor   Rapid Detection   Food Safety  

Fiber Optics-Based Surface Enhanced Raman Spectroscopy Sensors for Rapid Multiplex Detection of Foodborne Pathogens in Raw Poultry Academic Background Foodborne illnesses are a significant global public health challenge, with Salmonella being one of the leading pathogens causing such diseases. In the United States alone, Salmonella results in 1.35 ...

Fabrication and In Vivo Testing of a Sub-mm Duckbill Valve for Hydrocephalus Treatment

Medicine, Neurology, Neurosurgery, Life Sciences, Bioengineering,
hydrocephalus   duckbill valve   intracranial pressure   cerebrospinal fluid   shunting systems  

Fabrication and In Vivo Testing of a Sub-mm Duckbill Valve for Hydrocephalus Treatment Academic Background Hydrocephalus is a complex pathological condition characterized by the accumulation of cerebrospinal fluid (CSF) in the cranium due to an imbalance between CSF production and absorption. This accumulation leads to increased intracranial pressu...