Long-term Clinical and Safety Outcomes from a Single-site Phase 1 Study of Neural Stem Cell Transplantation for Chronic Thoracic Spinal Cord Injury Academic Background Spinal cord injury (SCI) is a severe neurological condition that causes significant disability in millions of people worldwide. Traditional treatments primarily focus on stabilizing ...

Research Report: Reshaping Functional Hierarchies in Medication-Refractory Essential Tremor Through MRgFUS Therapy Essential tremor (ET), a prevalent movement disorder, is characterized by involuntary limb tremors, particularly noticeable during specific tasks. While traditional pharmacological treatments and deep brain stimulation (DBS) have shown...

Crossing the Blood–Brain Barrier: Study on Adipose-Derived Stem Cells as Carriers for Pro-Apoptotic Oncolytic Myxoma Virus in the Treatment of Murine Glioblastoma Background and Objective Glioblastoma (GBM) is among the most invasive and aggressive brain tumors, characterized by high recurrence rates and poor prognosis. Despite multimodal intervent...

Fibrotic Response Induced by Anti-CSF-1R Treatment Promotes Glioblastoma Recurrence Background Introduction Glioblastoma (GBM) is a highly aggressive and malignant primary tumor of the central nervous system. Although current standard treatments include surgical resection, Temozolomide chemotherapy, and fractionated radiotherapy, the median surviva...

Long-term Neuropsychological Trajectories in Pediatric Epilepsy Patients: Can Surgery Prevent Decline? Patients with long-term drug-resistant epilepsy (DRE) often face severe neuropsychological functional impairments, especially in children, which can significantly impact their academic performance, social relationships, and future employment oppor...