Multicentre Prospective Study on the Diagnostic and Prognostic Validity of Malnutrition Assessment Tools in Surgery

Academic Background Malnutrition is a significant risk factor for postoperative complications, particularly in patients undergoing major abdominal surgery, where the incidence of malnutrition is high. However, there is currently no widely accepted tool for assessing malnutrition. Existing nutritional screening tools vary greatly in sensitivity and ...

Hydrogen Gas and the Gut Microbiota as Potential Biomarkers for the Development of Experimental Colitis in Mice

Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition that primarily includes Ulcerative Colitis (UC) and Crohn’s Disease (CD). The incidence of IBD has been increasing globally, imposing significant health and economic burdens on patients and society. Currently, the diagnosis of IBD relies mainly on endoscopy, but this method is exp...

GutBugDB: A Web Resource to Predict the Human Gut Microbiome-Mediated Biotransformation of Biotic and Xenobiotic Molecules

In recent years, the significant role of the human gut microbiota (HGM) in the metabolism of drugs and nutrients has gradually been recognized. The gut microbiota not only affects the bioavailability of orally administered drugs but also participates in the biotransformation of drugs and bioactive molecules through its metabolic enzymes, thereby in...

Megasphaera elsdenii, a Commensal Member of the Gut Microbiota, is Associated with Elevated Gas Production During In Vitro Fermentation

Flatulence is a common occurrence in daily life, often resulting from the fermentation of undigested food components by the gut microbiota. While flatulence is generally harmless, it can lead to discomfort, bloating, and even chronic conditions such as irritable bowel syndrome (IBS). Certain foods, particularly those rich in dietary fiber like bean...

The Effects of Fermented Vegetables on the Gut Microbiota for Prevention of Cardiovascular Disease

In recent years, the role of gut microbiota in health and disease has garnered widespread attention. Research indicates that the diversity and composition of gut microbiota are closely related to the development and progression of cardiovascular disease (CVD). CVD is one of the leading causes of death globally, and inflammation plays a significant ...