Hepatic Arterial Infusion Chemotherapy-Based Conversion Hepatectomy in Responders Versus Nonresponders with Hepatocellular Carcinoma: A Multicenter Cohort Study

Medicine, Hepatobiliary System, Oncology,
conversion hepatectomy   hepatic arterial infusion chemotherapy   hepatocellular carcinoma   tumor response   survival rate   surgical timing   multicenter study  

Hepatic Arterial Infusion Chemotherapy (HAIC)-Based Conversion Hepatectomy in Patients with Hepatocellular Carcinoma Academic Background Hepatocellular carcinoma (HCC) is one of the most common liver malignancies worldwide, particularly in China, where its incidence and mortality rates remain high. Despite advancements in treatment strategies, radi...

Observational Cohort Study on Safety and Efficacy of Robotic Thyroidectomy with Super-Meticulous Capsular Dissection versus Open Surgery for Thyroid Cancer: Postoperative Dynamic Risk Assessment of Radioactive Iodine Therapy

Medicine, Endocrinology, Oncology,
131I-WBS   hypoparathyroidism   radioactive iodine   robotic thyroidectomy   thyroid cancer  

Comparative Study of Robotic-Assisted Thyroidectomy versus Traditional Open Surgery in Thyroid Cancer Treatment Academic Background The incidence of thyroid cancer has been increasing annually, with differentiated thyroid carcinoma (DTC) accounting for over 90% of all thyroid cancer cases. Currently, the standard treatment for DTC includes surgical...

Reoperation for Ipsilateral Local Recurrence Following Prior Nephron-Sparing Surgery: Innovative Surgical Insights from a High-Volume Urological Center with Cross-Sectional Study

Medicine, Urology, Oncology,
local recurrence   nephron-sparing surgery   reoperation   surgical strategies   renal cell carcinoma   robotic-assisted surgery   laparoscopic surgery  

Innovative Surgical Strategies for Reoperation of Local Recurrence in Renal Cell Carcinoma Academic Background Renal cell carcinoma (RCC) is one of the most common malignant tumors in adults, accounting for 5% of malignancies in males and 3% in females. Although surgery remains the standard treatment for localized RCC, nephron-sparing surgery (NSS)...

Circulating Tumor DNA Trajectories Predict Survival in Trifluridine/Tipiracil-Treated Metastatic Colorectal Cancer Patients

Medicine, Oncology,
Circulating Tumor DNA   Metastatic Colorectal Cancer   Trifluridine/Tipiracil   Survival Rate   Molecular Biomarkers   Treatment Response   Prognosis  

ctDNA Trajectories Predict Survival in Trifluridine/Tipiracil-Treated Metastatic Colorectal Cancer Patients Academic Background Metastatic colorectal cancer (mCRC) is one of the leading causes of cancer-related deaths worldwide. Despite recent advancements in diagnosis and treatment, the prognosis for advanced-stage patients remains poor. Triflurid...

CM313 Monotherapy in Patients with Relapsed/Refractory Multiple Myeloma or Marginal Zone Lymphoma: A Multicenter, Phase 1 Dose-Escalation and Dose-Expansion Trial

Medicine, Hematology, Oncology,
Multiple Myeloma   Marginal Zone Lymphoma   CM313   Dose-Escalation   Safety   Efficacy   Clinical Trial  

CM313 Monotherapy in Patients with Relapsed/Refractory Multiple Myeloma or Marginal Zone Lymphoma: A Multicenter Phase 1 Dose-Escalation and Expansion Trial Academic Background Multiple Myeloma (MM) is a common hematologic malignancy, accounting for approximately one-tenth of all hematologic malignancies. Although the use of immunomodulatory drugs ...

Clinical Significance of Stratifying Prostate Cancer Patients Through Specific Circulating Genes

Medicine, Urology, Oncology,
prostate cancer   circulating genes   liquid biopsy   biomarker   drug target   neuroendocrine   stem cell  

Clinical Significance of Stratifying Prostate Cancer Patients Through Specific Circulating Genes Academic Background Prostate Cancer (PCA) is the most common cancer among men in North America and a leading cause of cancer-related mortality. Although many patients are diagnosed with organ-confined disease, 25-35% experience recurrence after curative...